Killer Cell Lectin-Like Receptor Subfamily C, Member 2 Proteins (KLRC2)

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily C, Member 2 Antibodies (59) and Killer Cell Lectin-Like Receptor Subfamily C, Member 2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KLRC2 3822 P26717
KLRC2 450132  
KLRC2 100125588  
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Top Killer Cell Lectin-Like Receptor Subfamily C, Member 2 Proteins at antibodies-online.com

Showing 6 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human His tag 50 μg Log in to see 2 to 3 Days
$375.00
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$736.00
Details
Yeast Rhesus Monkey His tag   1 mg Log in to see 60 to 71 Days
$2,293.50
Details
Yeast Chimpanzee His tag   1 mg Log in to see 60 to 71 Days
$2,299.00
Details
Wheat germ Human Un-conjugated   10 μg Log in to see 11 to 12 Days
$654.29
Details

KLRC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Chimpanzee

Rhesus Monkey

More Proteins for Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2) Interaction Partners

Human Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2) interaction partners

  1. a 16kb deletion encompassing the NKG2C gene is associated with lower carotid intimal media thickness values and higher humoral and T-cell responses to cytomegalovirus in renal transplant recipients

  2. the data of this study extend the characterization of adaptive NK cell subsets that differentiate in response to human Cytomegalovirus, supporting a relationship between their distribution and NKG2C copy number

  3. The new method offers the potential to use SNP arrays from genome wide association studies to study the frequency of KLRC2 deletion in other populations and its association with other diseases

  4. Assessment of NK cell repertoires in 60 NKG2C(-/-) donors revealed a broad range of NK cell populations displaying characteristic footprints of adaptive NK cells, including a terminally differentiated phenotype, functional reprogramming, and epigenetic remodeling of the interferon (IFN)-gamma (show IFNA Proteins) promoter.

  5. HLA-E (show HLAE Proteins) regulates NKG2C+ natural killer cell function through presentation of a restricted peptide repertoire

  6. Data suggest the proinflammatory potential of NKG2C(bright) NK cells.

  7. lack of expression of NKG2C may be associated with altered control of human cytomegalovirus infection in childhood

  8. No difference in the prevalence of NKG2C deletion was observed.

  9. NKG2C receptor deletion and a functional polymorphism in its ligand HLA-E may play a role in psoriasis susceptibility

  10. NKG2C(hi)CD57 (show B3GAT1 Proteins)+ NK cells respond specifically to acute infection with cytomegalovirus and not Epstein-Barr virus.

Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2) Protein Profile

Protein Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.

Gene names and symbols associated with KLRC2

  • killer cell lectin like receptor C2 (KLRC2)
  • killer cell lectin-like receptor subfamily C, member 2 (KLRC2)
  • CD159c protein
  • NKG2-C protein
  • NKG2C protein

Protein level used designations for KLRC2

CD159 antigen-like family member C , NK cell receptor C , NKG2-C type II integral membrane protein , NKG2-C-activating NK receptor , NKG2-FE

GENE ID SPECIES
3822 Homo sapiens
100125588 Macaca mulatta
450132 Pan troglodytes
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