Kruppel-Like Factor 8 (KLF8) ELISA Kits

KLF8 encodes a protein which is a member of the Sp/KLF family of transcription factors. Additionally we are shipping KLF8 Antibodies (54) and KLF8 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KLF8 KLF8 11279 O95600
Anti-Mouse KLF8 KLF8 245671 Q8BLM0
Anti-Rat KLF8 KLF8 302582  
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More ELISA Kits for KLF8 Interaction Partners

Zebrafish Kruppel-Like Factor 8 (KLF8) interaction partners

  1. Results demonstrate a novel role of Klf8, achieved via modulation of p53 (show TP53 ELISA Kits) and met expression, in the maintenance neuronal progenitors and development of Purkinje cells and the proliferation of granule cells in the cerebella of zebrafish embryos

Human Kruppel-Like Factor 8 (KLF8) interaction partners

  1. expression of miR (show MLXIP ELISA Kits)-1236-3p was lower in lung adenocarcinoma tissues than that in adjacent normal tissue; in A549 cell line, miR (show MLXIP ELISA Kits)-1236-3p decreased ability of cell invasion and migration; furthermore, KLF8 is targeted by miR (show MLXIP ELISA Kits)-1236-3p, and expression of miR (show MLXIP ELISA Kits)-1236-3p is negatively correlated with KLF8; additionally, miR (show MLXIP ELISA Kits)-1236-3p suppressed the expression of KLF8 and EMT (show ITK ELISA Kits) (epithelial mesenchymal transition)-related genes

  2. Overexpression of KLF8 may contribute to the progression of pancreatic cancer, and downregulation of KLF8 expression by lentivirus-delivered shRNA is a novel therapeutic approach for PC.

  3. KLF8 plays a crucial role in proliferation and migration of bladder cancer cells

  4. KLF8-induced FHL2 (show FHL2 ELISA Kits) activation is a novel and critical signaling mechanism underlying human colorectal cancer invasion and metastasis.

  5. KLF8 and miR141/EGFR (show EGFR ELISA Kits) have roles in signaling pathway potentially crucial for breast cancer malignancy

  6. KLF8 suppression induced cell differentiation and inhibited tumorigenesis in colorectal cancer

  7. MiR (show MLXIP ELISA Kits)-135a inhibits migration and invasion and regulates epithelial-mesenchymal transition-related marker genes by targeting KLF8 in lung cancer cells.

  8. KLF8 is a novel epithelial to mesenchymal transition regulating transcription factor that involved in the progression of gastric cancer.

  9. In this review, we focus on the functions, roles, and regulatory networks of these five KLFs in HCC (show FAM126A ELISA Kits), summarize key pathways, and propose areas for further investigation

  10. A novel KLF8 to EPSTI1 to VCP (show vcp ELISA Kits) to NF-kappaB (show NFKB1 ELISA Kits) signaling mechanism potentially critical for breast cancer invasion and metastasis.

Mouse (Murine) Kruppel-Like Factor 8 (KLF8) interaction partners

  1. Klf8 is highly expressed in various regions of the mouse brain and in particular in the neurons, where it was localized in the cell nuclei.

  2. KLF3 and KLF8 have overlapping roles in vivo and participate in the silencing of embryonic globin expression during development.

  3. KLF8 is a key component of the transcription factor network that controls terminal differentiation during adipogenesis.

  4. PARP-1 (show PARP1 ELISA Kits) as a novel KLF8-binding and -regulating protein and provided new insights into the mechanisms underlying the regulation of KLF8 nuclear localization, stability, and functions.

  5. These results identified the KLF8 activation domain located between residues 101-260 where the well-conserved Q118 and Q248 are essential for recruiting p300 (show NOTCH1 ELISA Kits) and PCAF (show KAT2B ELISA Kits) to activate target gene transcription.

  6. sumoylation of KLF8 negatively regulates its transcriptional activity and cellular functions

  7. Klf8 is repressed by Klf3 (show KLF3 ELISA Kits) and activated by Klf1 (show KLF1 ELISA Kits) in vivo.

  8. KLF8 has two N terminal regulatory regions, one surrounding S165 and K171 and the other being two tandem ZFs, which are critical for the regulation of KLF8 nuclear localization and its cellular functions

Pig (Porcine) Kruppel-Like Factor 8 (KLF8) interaction partners

  1. results demonstrate that KLF8 can participate in regulating expression of alternate forms of HuR (show ELAVL1 ELISA Kits) mRNA along with NF-kappaB (show NFKB1 ELISA Kits) and other factors, depending on cellular contexts

KLF8 Antigen Profile

Antigen Summary

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Kruppel-Like Factor 8 (KLF8) ELISA Kits

  • Kruppel like factor 8 (KLF8) antibody
  • Kruppel-like factor 8 (klf8) antibody
  • Kruppel-like factor 8 (Klf8) antibody
  • Kruppel-like factor 8 (KLF8) antibody
  • A830097P10Rik antibody
  • BKLF3 antibody
  • klf8 antibody
  • Klf8-ps1 antibody
  • RGD1565831 antibody
  • ZNF74 antibody
  • ZNF741 antibody

Protein level used designations for Kruppel-Like Factor 8 (KLF8) ELISA Kits

Krueppel-like factor 8 , kruppel-like factor 8 , Kruppel-like factor 8 , basic krueppel-like factor 3 , basic kruppel-like factor 3 , zinc finger protein 741 , Kruppel-like factor 8, pseudogene 1

100051239 Equus caballus
562805 Danio rerio
100351857 Oryctolagus cuniculus
11279 Homo sapiens
245671 Mus musculus
302582 Rattus norvegicus
100154631 Sus scrofa
430697 Gallus gallus
525558 Bos taurus
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