anti-L-2-Hydroxyglutarate Dehydrogenase (L2HGDH) Antibodies

L2HGDH encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Additionally we are shipping L2HGDH Kits (5) and L2HGDH Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
L2HGDH 314196  
L2HGDH 79944 Q9H9P8
L2HGDH 217666 Q91YP0
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Top anti-L2HGDH Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: L2HGDH Sample Type: HepG2 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (35ug/lane) using L2HGDH/Duranin Antibody . This demonstrates the L2HGDH antibody detected the L2HGDH protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB L2HGDH Antibody (Center) (ABIN654213) western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (35 µg/lane). This demonstrates the L2HGDH antibody detected the L2HGDH protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IHC, WB ABIN6273003 at 1/100 staining Human brain cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of SGC-7901 cells, using L2HGDH antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of mouse kidney and mouse heart cells, using L2HGDH antibody. Immunohistochemistry of paraffin-embedded human gastric using L2HGDH antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 16 Days
$334.77
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using L2HGDH antibody. Immunohistochemistry of paraffin-embedded human stomach using L2HGDH antibody. 120 μL Log in to see 12 to 14 Days
$251.90
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μL Log in to see 7 to 9 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 11 to 18 Days
$369.55
Details

More Antibodies against L2HGDH Interaction Partners

Human L-2-Hydroxyglutarate Dehydrogenase (L2HGDH) interaction partners

  1. The mutations of the L2HGDH gene as the causes of L-2-hydroxyglutaric aciduria.

  2. c.845G>A (p.R282Q) in the exon 7 of the L2HGDH gene is associated with 2-hydroxyglutaric aciduria in Chinese family.

  3. Intragenic single nucleotide length polymorphisms and two extragenic microsatellites flanking the L2HGDH gene confirm the founder effect of c.241A>G mutation in the 14 studied cases.

  4. Report ten novel mutations in the L2HGDH gene in patients with L-2-hydroxyglutaric aciduria from different ethnic backgrounds.

  5. L2HGDH mutation is not associated with glioblastoma.

  6. We did not find evidence for mutations in the genes D2HGDH (show D2HGDH Antibodies) and L2HGDH as an alternative mechanism for raised 2-hydroxyglutarate levels in brain tumours

  7. Exonic mutations in the L2HGDH gene in Staffordshire bull terriers have been identified and associated with epilepsy.

  8. we present three novel mutations (Gln197X, Gly211Val and c.540+1 G>A), which increase the present deleterious collection of L2HGDH gene up to 35 mutationsthat we have compiled in this study.

  9. encodes a putative mitochondrial protein (show COX6B2 Antibodies) with homology to FAD (show BRCA2 Antibodies)-dependent oxidoreductases; a mutant gene is accociated with L-2-hydroxyglutaric aciduria.propose to name the gene duranin

  10. data indicate that l-2-hydroxyglutaric aciduria is due to a deficiency in l-2-hydroxyglutarate dehydrogenase

Mouse (Murine) L-2-Hydroxyglutarate Dehydrogenase (L2HGDH) interaction partners

  1. L2hgdh mutation leads to l-2-hydroxyglutarate accumulation, leukoencephalopathy, and neurodegeneration in mice.

  2. Data describe a mouse model of L-2-hydroxyglutaric aciduria where mouse with l2hgdh gene deficiency accumulates toxic levels of L-2-hydroxyglutarate mostly in brain and testis and shows significant brain spongiosis and learning deficit.

L2HGDH Antigen Profile

Protein Summary

This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

Gene names and symbols associated with L2HGDH

  • L-2-hydroxyglutarate dehydrogenase (L2hgdh) antibody
  • L-2-hydroxyglutarate dehydrogenase (L2HGDH) antibody
  • BC016226 antibody
  • C14orf160 antibody
  • RGD1306250 antibody

Protein level used designations for L2HGDH

L-2-hydroxyglutarate dehydrogenase, mitochondrial , 2-hydroxyglutarate dehydrogenase , L-alpha-hydroxyglutarate dehydrogenase , alpha-hydroxyglutarate oxidoreductase , alpha-ketoglutarate reductase , duranin

GENE ID SPECIES
314196 Rattus norvegicus
79944 Homo sapiens
217666 Mus musculus
514230 Bos taurus
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