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Acts in asparagine catabolism. Additionally we are shipping L-Asparaginase Proteins (6) and L-Asparaginase Kits (3) and many more products for this protein.
Showing 9 out of 10 products:
A panel including p53 (show TP53 Antibodies) and ASRGL1 (show ASRGL1 Antibodies) immunohistochemistry was identified as the most accurate predictor of relapse-free and disease-specific survival. Within this panel, patients were allocated into high- (5.9%), intermediate- (29.5%) and low- (64.6%) risk groups where high-risk patients had a 30-fold risk (P<0.001) of dying of EEC compared to the low-risk group.
In a prospective setting ASRGL1 (show ASRGL1 Antibodies) validates as a strong prognostic biomarker in endometrial carcinoma. Loss of ASRGL1 (show ASRGL1 Antibodies) is associated with aggressive disease and poor survival.
Our studies suggest that the p.G178R mutation in ASRGL1 (show ASRGL1 Antibodies) leads to photoreceptor degeneration resulting in progressive vision loss.
Multiple negatively charged small molecules interact within the active site of ASRGL1 (show ASRGL1 Antibodies) to act as a base in promoting cleavage.
Reduced expression of ASRGL1 (show ASRGL1 Antibodies), defined as <75% positively stained tumor cells, was significantly associated with poor prognosis and reduced disease-specific survival in endometrioid endometrial adenocarcinoma (EEA).
Human ALP (show ALP Antibodies) cDNA was subsequently cloned. It showed 77% identity to the rat ALP (show ALP Antibodies) sequence and the gene, ASRGL1 (asparaginase-like 1 (show ASRGL1 Antibodies)), mapped to chromosome locus 11q12.3.
ASRGL1 (show ASRGL1 Antibodies) exhibits beta-aspartyl peptidase activity consistent with plant-type asparaginases. ASRGL1 (show ASRGL1 Antibodies) is shown to be an Ntn (show NRTN Antibodies) hydrolase for which Thr168 serves as the essential N-terminal nucleophile for intramolecular processing and catalysis.
Acts in asparagine catabolism. May be involved in astroglial production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions (By similarity).
, L-asparagine amidohydrolase
, asparaginase-like 1 protein
, asparaginase-like protein 1
, isoaspartyl dipeptidase
, isoaspartyl peptidase/L-asparaginase
, asparaginase-like 1
, asparaginase-like sperm autoantigen
, glial asparaginase