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The protein encoded by LRBA is a member of the WDL-BEACH-WD (WBW) gene family. Additionally we are shipping LRBA Antibodies (17) and LRBA Proteins (2) and many more products for this protein.
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The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene.
, lipopolysaccharide-responsive and beige-like anchor protein
, CDC4-like protein
, vesicle trafficking, beach and anchor containing