anti-Latexin (LXN) Antibodies

LXN encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. Additionally we are shipping Latexin Proteins (24) and Latexin Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LXN 56925 Q9BS40
LXN 17035 P70202
LXN 59073 Q64361
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Top anti-Latexin Antibodies at antibodies-online.com

Showing 10 out of 171 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>Host: </b>Rabbit<br><b>Target Name: </b>LXN<br><b>Antibody Dilution: </b>1.0ug/ml<br><b>Sample Tissue: </b>A549 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN190839 (0.1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded FaDu xenograft, using LXN, antibody at 1:500 dilution. WB Image Sample(30 ug whole cell lysate) A:293T B:HeLa S3, 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Mouse Mouse Un-conjugated WB LXN antibody   western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the LXN  antibody detected the LXN  protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Latexin Antibody [NBP1-86079] - Staining of human prostate shows strong cytoplasmic and nuclear positivity in glandular cells. Western Blot: Latexin Antibody [NBP1-86079] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10 Lane 2: Mouse Cerebral Cortex tissue 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Immunohistochemistry-Paraffin: LXN Antibody [NBP1-32525] - Paraffin-embedded FaDu xenograft, using antibody at 1:500 dilution. Immunocytochemistry/Immunofluorescence: LXN Antibody [NBP1-32525] - Paraformaldehyde-fixed mouse ESC D3, using antibody at 1:200 dilution. 100 μL Log in to see 7 to 9 Days
$514.63
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Mouse Lung Tissue; Lane2: Human Hela Cells. 100 μg Log in to see 13 to 16 Days
$380.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of Latexin (arrow) using rabbit polyclonal Latexin Antibody (Center) (ABIN388260). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the LXN gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with Latexin antibody (Center) (ABIN388260), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details

LXN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Latexin Antibodies

  1. Human Polyclonal Latexin Primary Antibody for IHC, ELISA - ABIN190839 : de Haan: Latexin is a newly discovered regulator of hematopoietic stem cells. in Nature genetics 2007 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal Latexin Primary Antibody for IHC (p), IHC - ABIN252922 : Kadouchi, Sakamoto, Tangjiao, Murakami, Kobayashi, Hoshino, Yamaguchi: Latexin is involved in bone morphogenetic protein-2-induced chondrocyte differentiation. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal Latexin Primary Antibody for IHC - ABIN966502 : Pallarès, Bonet, García-Castellanos, Ventura, Avilés, Vendrell, Gomis-Rüth: Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

  4. Human Polyclonal Latexin Primary Antibody for IHC, IHC (p) - ABIN4330408 : Muthusamy, Premi, Soper, Platt, Bosenberg: The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma. in The Journal of investigative dermatology 2013 (PubMed)

More Antibodies against Latexin Interaction Partners

Human Latexin (LXN) interaction partners

  1. Results identified that LXN expression inversely modulates taxane-chemoresistance in the PC-3 (show PCSK1 Antibodies) prostate cancer cell line. Inhibition of LXN expression in the bone microenvironment promotes chemoresistance, in part through a methylation-dependent mechanism.

  2. Results show that Lxn expression was clearly decreased in the pancreatic ductal adenocarcinoma tissues suggesting it that as a tumor suppressor that targets CD133-positive cancer cells.

  3. Lxn protein and mRNA expression levels in CD133+ miapaca-2 cells were significantly lower than those in CD133- cells.

  4. latexin is markedly downregulated in hepatocellular carcinoma specimens, compared to adjacent non-cancerous tissues.

  5. CD146 (show MCAM Antibodies) and Lxn increased tumor migration and invasion of thyroid cancer.

  6. The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma.

  7. These results are consistent with a tumor suppressor role for latexin.

  8. Latexin expression is lost or greatly reduced in approximately 50% of human leukemia/lymphoma cell lines.

Mouse (Murine) Latexin (LXN) interaction partners

  1. By using an Lxn knockout mouse model, this study found that Lxn inactivation in vivo led to the physiological expansion of the entire hematopoietic hierarchy. Loss of Lxn enhanced the competitive repopulation capacity and survival of hematopoietic stem cells in a cell-intrinsic manner.

  2. Rps3 (show RPS3 Antibodies) knockdown increased the radiation sensitivity of FDC-P1, confirming that the mechanism of action of Lxn is mediated by Rps3 (show RPS3 Antibodies) pathway.

  3. These results are consistent with a tumor suppressor role for latexin.

  4. Latexin is preferentially expressed in hematopoietic stem cells, and is co-localized with the molecules responsible for the interaction of hematopoietic stem cells with a bone marrow niche.

  5. Data indicate that AAV-mediated latexin transduction or administration of a small molecule carboxypeptidase A inhibitor significantly reduced acetone-evoked nociceptive behavior after SNI.

  6. The crystal structure of mouse latexin, solved at 1.83 A resolution, shows no structural relationship with other carboxypeptidase inhibitors.

  7. Latexin is involved in the transmission of pain, since mice lacking this protein experience reducted pain sensitivity.

  8. promoter polymorphisms between the B6 and D2 alleles may affect Lxn gene expression and consequently influence the population size of hematopoietic stem cells.

  9. These results indicate that latexin is involved in BMP-2 (show BMP2 Antibodies)-induced chondrocyte differentiation and plays an important role in skeletogenesis and skeletal regeneration.

Latexin (LXN) Antigen Profile

Protein Summary

This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases.

Gene names and symbols associated with anti-Latexin (LXN) Antibodies

  • latexin (lxn) antibody
  • latexin (LXN) antibody
  • latexin (Lxn) antibody
  • ECI antibody
  • lxn antibody
  • TCI antibody
  • wu:fk66c02 antibody
  • zgc:103612 antibody

Protein level used designations for anti-Latexin (LXN) Antibodies

latexin , Latexin , MUM , endogenous carboxypeptidase inhibitor , tissue carboxypeptidase inhibitor , ECI , TCI

GENE ID SPECIES
494053 Danio rerio
703996 Macaca mulatta
771519 Gallus gallus
100195080 Salmo salar
100322883 Felis catus
100346216 Oryctolagus cuniculus
56925 Homo sapiens
17035 Mus musculus
59073 Rattus norvegicus
610062 Canis lupus familiaris
781644 Bos taurus
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