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Negatively regulates growth hormone (GH) receptor cell surface expression in liver. Additionally we are shipping LEPROTL1 Proteins (3) and many more products for this protein.
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Transgenic mice expressing either human LEPROT or human LEPROTL1 displayed growth retardation, reduced plasma IGF1 levels, and impaired hepatic sensitivity to GH, as measured by STAT5 phosphorylation and Socs2 mRNA expression.
Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
leptin receptor overlapping transcript-like 1
, Leptin receptor overlapping transcript-like 1