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May be involved in the activation of cells of innate and acquired immunity (By similarity).. Additionally we are shipping LRRC25 Proteins (10) and many more products for this protein.
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Our study has not only identified LRRC25 as a novel inhibitor of NF-kappaB signaling pathway, but also uncovers a new mechanism of crosstalk between NF-kappaB signaling and autophagy pathways.
LRRC25 as a critical molecular switch whose down-regulation resulted in cardiac hypertrophy in a TGF-beta1- and NF-kappaB-dependent manner.
The findings identify a previously unrecognized role of LRRC25 in type I interferon signaling activation by which LRRC25 acts as a secondary receptor to assist RIG-I delivery to autophagosomes for degradation in a p62-dependent manner.
May be involved in the activation of cells of innate and acquired immunity (By similarity).
leucine-rich repeat-containing protein 25
, monocyte and plasmacytoid activated molecule
, monocyte and plasmacytoid-activated protein