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LZTFL1 encodes a ubiquitously expressed protein that localizes to the cytoplasm. Additionally we are shipping Leucine Zipper Transcription Factor-Like 1 Antibodies (73) and many more products for this protein.
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This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome\; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor\; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.
leucine zipper transcription factor-like 1
, Leucine zipper transcription factor-like protein 1
, leucine zipper transcription factor-like protein 1