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LIPC encodes hepatic triglyceride lipase, which is expressed in liver. Additionally we are shipping Lipase, Hepatic Antibodies (98) and Lipase, Hepatic Kits (55) and many more products for this protein.
Showing 10 out of 15 products:
Human LIPC Protein expressed in HEK-293 Cells - ABIN2712314
Ma, Paik, Barile: Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway. in Investigative ophthalmology & visual science 2014
The expression of hHL promoted hepatic triglyceride accumulation and de novo lipogenesis without affecting triglyceride secretion, and this was associated with an upregulation of Srebf1 (show SREBF1 Proteins) as well as the main genes controlling the synthesis of fatty acids. Transgenic mice also exhibited more adiposity and an increased LPL (show LCP1 Proteins)-mediated FFA influx into the WAT without affecting glucose tolerance
LPL (show LCP1 Proteins) is important for the maturation of small discoidal HDL (show HSD11B1 Proteins) particles into large spherical HDL (show HSD11B1 Proteins) particles, while HL is important for HDL (show HSD11B1 Proteins) remodeling of very large HDL (show HSD11B1 Proteins) particles into intermediate-size HDL (show HSD11B1 Proteins) particles, as shown in lipoprotein lipase (show LPL Proteins) and hepatic lipase deficiency
The expression level of LIPC, SLC16A8, and TIMP-3 (show TIMP3 Proteins) was significantly associated with age-related macular degeneration pathology.
We found inverse independent correlations between metabolic clearance rate of insulin (show INS Proteins) (MCRI) and hepatic lipase (P = 0.0004), insulin (show INS Proteins) secretion (P = 0.0002), alanine aminotransferase (show ALT Proteins) (P = 0.0045), total fat mass (P = 0.014), and diabetes (P = 0.03). MCRI and apolipoprotein A-I (show APOA1 Proteins) exhibited a positive independent correlation (P = 0.035).
Hepatic lipase activity increases after levothyroxine therapy in subclincal hypothyroidism and can be interpreted as a possible explanation for the decrease in remnant-like lipoprotein cholesterol.
The hepatic lipase (LIPC) rs10468017 variant was associated with a significantly decreased risk of AMD (show AMD1 Proteins)
the association between LIPC C-514T polymorphism, obesity and plasma lipid profile in Chinese children and adolescents, is reported.
results show that SM is a physiological inhibitor of HL activity in lipoproteins and that the specificity of the enzyme towards HDL (show HSD11B1 Proteins) is at least partly due to its low SM content.
The role of hepatic triglyceride lipase (show LIPG Proteins) in remnant lipoprotein metabolism.
Dietary fat intake significantly modified the LIPC genetic effect on changes in serum triglyceride, LDL cholesterol, and HDL (show HSD11B1 Proteins) cholesterol concentrations during a 2-y randomized weight-loss intervention trial.
The LIGHT (Tumour necrosis factor (show TNF Proteins) ligand superfamily member 14, TNFSF14 (show TNFSF14 Proteins))/Lymphotoxin beta-Receptor (show LTBR Proteins)(LTbeta (show LTB Proteins)-R) pathway, which is involved in T-cell and macrophage activation, was diminished in plasma and in apoE (show APOE Proteins)-/-Irs2 (show IRS2 Proteins)+/-HL-/- atheromas.
hepatic lipase KO mice had dyslipidemia including hypercholesterolemia, hypertriglyceridemia and increased non-esterified fatty acid levels. Also glucose intolerance, pancreatic and hepatic inflammation and steatosis.
Bone marrow (BM)-derived hepatic lipase mitigates the HDL (show HSD11B1 Proteins)-lowering, HDL (show HSD11B1 Proteins)-modulating, and cholesterol-raising effects of BM-derived cholesteryl ester transfer protein (show CETP Proteins).
HL expressed by osteoblasts has an impact on osteoblast OPG (show TNFSF11 Proteins) expression and that lack of HL leads to increased bone mass.
Hepatic lipase and endothelial lipase (show LIPG Proteins) influence molecular species of several classes of plasma lipids.
interaction of LIGHT with LTbetaR on hepatocytes, but not Kupffer cells, is sufficient to down regulate hepatic lipase expression and that this effect can be independent of LIGHT's costimulatory function.
Hepatic lipase- and endothelial lipase (show LIPG Proteins)-deficiency in mice promotes macrophage-to-feces RCT (show FOXE3 Proteins) and HDL (show HSD11B1 Proteins) antioxidant properties.
Data show a novel pathway involving HL hydrolysis of VLDL that activates PPARdelta (show PPARD Proteins) through generation of specific monounsaturated fatty acids.
These results demonstrated that fatty acid synthase (show FASN Proteins) and hepatic lipase might be FXR (show NR1H4 Proteins)-regulated genes in liver cells.
The additive effect of hepatic lipase and endothelial lipase (show LIPG Proteins) on HDL (show HSD11B1 Proteins) metabolism but not macrophage reverse cholesterol transport in mice.
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake.
hepatic triacylglycerol lipase
, hepatic triglyceride lipase
, lipase, hepatic
, lipase C
, hepatic lipase
, hepatic triacylglycerol lipase-like
, lipase member C