MAX Dimerization Protein 4 Proteins (MXD4)

MXD4 is a member of the MAD gene family .

list all proteins Gene Name GeneID UniProt
Human MXD4 MXD4 10608 Q14582
Rat MXD4 MXD4 360961  
Mouse MXD4 MXD4 17122  
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Top MAX Dimerization Protein 4 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see Available
$284.90
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Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
Details
Escherichia coli (E. coli) Human DYKDDDDK Tag   10 μg Log in to see 1 to 2 Days
$460.83
Details

More Proteins for MAX Dimerization Protein 4 (MXD4) Interaction Partners

Human MAX Dimerization Protein 4 (MXD4) interaction partners

  1. The E3 ligase activity of c-IAP1 (show BIRC2 Proteins) was not required for downregulation of Mad4 expression.

  2. regulation by a transcriptional repressor complex that contains Miz-1 (show ZBTB17 Proteins) and c-Myc (show MYC Proteins)

  3. Data suggest that the biological function of the interaction between T-complex protein 10-like and MAD4 may be to maintain the differentiation state in liver cells.

  4. replicative senescence-specific factors may block c-Myc (show MYC Proteins) inhibition of Miz-1 (show ZBTB17 Proteins) activation of hMad4 expression, and the continual presence of hMad4 protein may transcriptionally repress selected c-Myc (show MYC Proteins) target genes

Mouse (Murine) MAX Dimerization Protein 4 (MXD4) interaction partners

  1. during embryonic hematopoietic differentiation Mxd4 is an important player in the regulation of blood progenitor proliferation, and downregulation of its expression might be required for a proliferative burst preceding lineage specification.

  2. Mxd4 and Mnt upregulation following OX40 (show TNFRSF4 Proteins) engagement most likely increases T-cell survival

  3. regulation by a transcriptional repressor complex that contains Miz-1 (show ZBTB17 Proteins) and c-Myc (show MYC Proteins)

MAX Dimerization Protein 4 (MXD4) Protein Profile

Protein Summary

This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.

Gene names and symbols associated with MXD4

  • MAX dimerization protein 4 (MXD4)
  • Max dimerization protein 4 (Mxd4)
  • MAX dimerization protein 4 S homeolog (mxd4.S)
  • microRNA 4800 (MIR4800)
  • MAX dimerization protein 4 (mxd4)
  • MAX dimerization protein 4 (Mxd4)
  • 2810410A03Rik protein
  • bhlhc12 protein
  • Mad4 protein
  • MGC84841 protein
  • mst149 protein
  • mstp149 protein
  • MXD4 protein
  • xmad4 protein

Protein level used designations for MXD4

Mad4 homolog , class C basic helix-loop-helix protein 12 , max dimerization protein 4 , max dimerizer 4 , max-associated protein 4 , max-interacting transcriptional repressor MAD4 , MAX dimerization protein 4 , basic helix-loop-helix transcription factor XMad4-236 , MAD4 , putative basic helix-loop-helix transcription factor variant 3

GENE ID SPECIES
10608 Homo sapiens
360961 Rattus norvegicus
403397 Xenopus laevis
422890 Gallus gallus
461074 Pan troglodytes
488803 Canis lupus familiaris
100124794 Xenopus (Silurana) tropicalis
100190457 Taeniopygia guttata
17122 Mus musculus
541116 Bos taurus
100733796 Cavia porcellus
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