MAX-Like Protein X Proteins (MLX)

The product of MLX belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. Additionally we are shipping MAX-Like Protein X Antibodies (95) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MLX 21428 O08609
MLX 6945 Q9UH92
Rat MLX MLX 360631  
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Top MAX-Like Protein X Proteins at

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days

MLX Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for MAX-Like Protein X (MLX) Interaction Partners

Mouse (Murine) MAX-Like Protein X (MLX) interaction partners

  1. MLX promotes myogenesis not via an adjustment of glucose metabolism but rather by inducing the expression of several myokines, including insulin-like growth factor 2 (IGF2 (show IGF2 Proteins))

  2. Glucose is required at two additional steps to stimulate the transcription activation function of MondoA (show MLXIP Proteins)-Mlx complexes.

  3. Overexpression of dominant negative Mlx improves glucose intolerance by inhibiting expression not only of lipogenic enzymes but also other important genes such as Glucose-6-phosphatase and Elovl6.

Human MAX-Like Protein X (MLX) interaction partners

  1. MYC (show MYC Proteins) is part of a network of bHLHLZ proteins centered on the MYC (show MYC Proteins) heterodimeric partner MAX and its counterpart, the MAX-like protein MLX.

  2. Knockdown of MondoA (show MLXIP Proteins), or its dimerization partner Mlx, blocks Myc (show MYC Proteins)-induced reprogramming of multiple metabolic pathways, resulting in apoptosis

  3. Data show that for both MondoA (show MLXIP Proteins) and Mlx, the C-terminal domain CRM-1 (show XPO1 Proteins) has cytoplasmic localization activity that is required by the protein monomers to accumulate in the cytoplasm.

  4. Mlx is an obligatory partner of ChREBP (show MLXIPL Proteins) in regulating lipogenic enzyme genes in liver.

  5. Endogenous MondoA (show MLXIP Proteins) and Mlx associate with mitochondria in primary skeletal muscle.

MAX-Like Protein X (MLX) Protein Profile

Protein Summary

The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with MAX-Like Protein X Proteins (MLX)

  • MLX, MAX dimerization protein (MLX)
  • MAX-like protein X (Mlx)
  • MLX, MAX dimerization protein (mlx)
  • MLX, MAX dimerization protein (Mlx)
  • max-like protein X (LOC786043)
  • bHLHd13 protein
  • DKFZp468J1719 protein
  • im:7146242 protein
  • MAD7 protein
  • MXD7 protein
  • TCFL4 protein
  • wu:fb61a01 protein
  • wu:fb99c01 protein
  • zgc:112409 protein

Protein level used designations for MAX-Like Protein X Proteins (MLX)

MAX-like protein X , transcription factor-like protein 4 , max-like protein X , BigMax alpha , MAX-like bHLHZIP protein , protein BigMax , transcription factor like 4 , transcription factor-like 4 , transcription factor max-like protein X , TF4 , BigMax protein , class D basic helix-loop-helix protein 13 , max-like factor protein

454691 Pan troglodytes
710570 Macaca mulatta
100174650 Pongo abelii
21428 Mus musculus
420026 Gallus gallus
607668 Canis lupus familiaris
554119 Danio rerio
508531 Bos taurus
6945 Homo sapiens
360631 Rattus norvegicus
786043 Bos taurus
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