Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The product of MLX belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. Additionally we are shipping MAX-Like Protein X Antibodies (95) and many more products for this protein.
Showing 4 out of 6 products:
MLX promotes myogenesis not via an adjustment of glucose metabolism but rather by inducing the expression of several myokines, including insulin-like growth factor 2 (IGF2 (show IGF2 Proteins))
Glucose is required at two additional steps to stimulate the transcription activation function of MondoA (show MLXIP Proteins)-Mlx complexes.
Overexpression of dominant negative Mlx improves glucose intolerance by inhibiting expression not only of lipogenic enzymes but also other important genes such as Glucose-6-phosphatase and Elovl6.
MYC (show MYC Proteins) is part of a network of bHLHLZ proteins centered on the MYC (show MYC Proteins) heterodimeric partner MAX and its counterpart, the MAX-like protein MLX.
Knockdown of MondoA (show MLXIP Proteins), or its dimerization partner Mlx, blocks Myc (show MYC Proteins)-induced reprogramming of multiple metabolic pathways, resulting in apoptosis
Data show that for both MondoA (show MLXIP Proteins) and Mlx, the C-terminal domain CRM-1 (show XPO1 Proteins) has cytoplasmic localization activity that is required by the protein monomers to accumulate in the cytoplasm.
Mlx is an obligatory partner of ChREBP (show MLXIPL Proteins) in regulating lipogenic enzyme genes in liver.
Endogenous MondoA (show MLXIP Proteins) and Mlx associate with mitochondria in primary skeletal muscle.
The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
MAX-like protein X
, transcription factor-like protein 4
, max-like protein X
, BigMax alpha
, MAX-like bHLHZIP protein
, protein BigMax
, transcription factor like 4
, transcription factor-like 4
, transcription factor max-like protein X
, BigMax protein
, class D basic helix-loop-helix protein 13
, max-like factor protein