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The protein encoded by MOB1B is similar to the yeast Mob1 protein.
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Mob1A (show MOBKL1B Proteins) and Mob1B are needed for cell abscission and centriole re-joining after telophase and cytokinesis.
MOB1A (show MOBKL1B Proteins) and MOB1B have overlapping functions in skin homeostasis, and exert their roles as tumor suppressors by regulating downstream elements of the Hippo pathway.
MOBKL1A/MOBKL1B (show MOBKL1B Proteins) phosphorylation, by MST1 (show MST1 Proteins) and MST2 (show STK3 Proteins), is sufficient to inhibit proliferation through actions at several points in the cell cycle.
Mst1 (show MST1 Proteins)/2-catalyzed MOBKL1A/B phosphorylation slows proliferation and is therefore a likely contributor to the anti-proliferative action of Mst1 (show MST1 Proteins) in naive T cells
The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene.
MOB1, Mps One Binder kinase activator-like 1A
, mps one binder kinase activator-like 1A
, MOB1, Mps One Binder kinase activator-like 1A, genome duplicate a
, MOB1, Mps One Binder kinase activator-like 1A (yeast)
, Mps one binder kinase activator-like 1A
, mps one binder kinase activator-like 1a
, kinase regulatory subunit MOB1B
, MOB1 Mps One Binder homolog B
, mob1 homolog 1A