Mago-Nashi Homolog, Proliferation-Associated (Drosophila) Proteins (MAGOH)

Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. Additionally we are shipping Mago-Nashi Homolog, Proliferation-Associated (Drosophila) Antibodies (72) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAGOH 4116 P61326
MAGOH 17149 P61327
MAGOH 298385 Q27W02
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Top Mago-Nashi Homolog, Proliferation-Associated (Drosophila) Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$286.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Yeast REACT_Atlantic Salmon His tag   1 mg Log in to see 60 to 71 Days
$2,321.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$2,317.33
Details
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$2,317.33
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,317.33
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,317.33
Details
Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$2,321.00
Details

MAGOH Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Mago-Nashi Homolog, Proliferation-Associated (Drosophila) (MAGOH) Interaction Partners

Human Mago-Nashi Homolog, Proliferation-Associated (Drosophila) (MAGOH) interaction partners

  1. findings show 2 genes MAGOH and MAGOHB (show MAGOHB Proteins) are expressed in mammals; in macrophages, expression of MAGOHB (show MAGOHB Proteins) but not MAGOH mRNA increases after LPS (show IRF6 Proteins) stimulation; both MAGOH proteins interact with other exon junction complex (EJC) components, incorporate into mRNA-bound EJCs and activate nonsense-mediated decay

  2. The stable association of multiprotein exon junction complex core with RNA is maintained by inhibition of eIF4AIII (show EIF4A3 Proteins) ATPase activity by MAGOH-Y14 (show RBM8A Proteins).

  3. crystal structure of a tetrameric exon junction core complex containing the DEAD-box adenosine triphosphatase eukaryotic initiation factor 4AIII (show EIF4A3 Proteins) bound to an ATP analog, MAGOH, Y14 (show RBM8A Proteins), a fragment of MLN51 (show CASC3 Proteins), and a polyuracil mRNA mimic

  4. These results indicate that MAGOH regulates the transcriptional activation of STAT3 (show STAT3 Proteins) by interfering complex formation between STAT3 (show STAT3 Proteins) and Y14 (show RBM8A Proteins).

Mouse (Murine) Mago-Nashi Homolog, Proliferation-Associated (Drosophila) (MAGOH) interaction partners

  1. we first show that Eif4a3 (show EIF4A3 Proteins) haploinsufficiency phenocopies aberrant neurogenesis and microcephaly of Magoh and Rbm8a (show RBM8A Proteins) mutant mice.we show that genetic ablation of one downstream pathway, p53 (show TP53 Proteins), significantly rescues microcephaly of all 3 EJC mutant

  2. findings show 2 genes MAGOH and MAGOHB (show MAGOHB Proteins) are expressed in mammals; in macrophages, expression of MAGOHB (show MAGOHB Proteins) but not MAGOH mRNA increases after LPS (show TLR4 Proteins) stimulation; both MAGOH proteins interact with other exon junction complex (EJC) components, incorporate into mRNA-bound EJCs and activate nonsense-mediated decay

  3. These results point to a central role for Magoh in melanocyte development.

  4. mouse magoh is involved in cyclin-dependent kinase (show CDK1 Proteins) regulation.

  5. Magoh haploinsufficiency causes microcephaly because of intermediate neural progenitors depletion and neuronal apoptosis.

Zebrafish Mago-Nashi Homolog, Proliferation-Associated (Drosophila) (MAGOH) interaction partners

  1. Zygotic mago nashi is expressed into the dorsal-marginal region during gastrulation.

Fruit Fly (Drosophila melanogaster) Mago-Nashi Homolog, Proliferation-Associated (Drosophila) (MAGOH) interaction partners

  1. MAPK (show MAPK1 Proteins) is the primary functional target of mago in eye development; in cultured cells, Mago knockdown disproportionately affects other large genes located in heterochromatin

  2. Mago Nashi, Tsunagi/Y14 (show RBM8A Proteins), and Ranshi form a complex that influences oocyte differentiation in Drosophila melanogaster

  3. We have determined the crystal structure of the complex between Drosophila melanogaster Y14 (show RBM8A Proteins) and Mago at a resolution of 2.5 A. The structure reveals an atypical mode of protein-protein recognition mediated by an RNA-binding domain (RBD (show CACNA1D Proteins)).

  4. mago nashi is required for germline stem cell differentiation, but surprisingly mago nashi functions independently of tsunagi/Y14 (show RBM8A Proteins) in this process

Mago-Nashi Homolog, Proliferation-Associated (Drosophila) (MAGOH) Protein Profile

Protein Summary

Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts.

Gene names and symbols associated with MAGOH

  • mago homolog, exon junction complex core component (MAGOH)
  • mago homolog, exon junction complex core component (Magoh)
  • protein mago nashi homolog (LOC736868)
  • mago homolog, exon junction complex core component (magoh)
  • mago homolog, exon junction complex core component L homeolog (magoh.L)
  • mago nashi (mago)
  • protein mago nashi homolog (LOC106584057)
  • CG9401 protein
  • Dmel\CG9401 protein
  • DmMago protein
  • Dm MGN protein
  • l(2)57Ca protein
  • Mago protein
  • Mago-m protein
  • magoh protein
  • MAGOH1 protein
  • MAGOHA protein
  • mgn protein
  • Mos2 protein
  • xl-mago protein
  • zgc:112220 protein

Protein level used designations for MAGOH

protein mago nashi homolog , mago-nashi-like proliferation-associated protein , mago-nashi homolog, proliferation-associated (Drosophila) , mago nashi , xl-mago , CG9401 gene product from transcript CG9401-RA , CG9401-PA , mago nishi , mago-PA , mago-nashi , mago nashi homolog

GENE ID SPECIES
4116 Homo sapiens
17149 Mus musculus
298385 Rattus norvegicus
479562 Canis lupus familiaris
505417 Bos taurus
736868 Pan troglodytes
100005893 Danio rerio
100038130 Xenopus (Silurana) tropicalis
379411 Xenopus laevis
37402 Drosophila melanogaster
100727610 Cavia porcellus
106584057 Salmo salar
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