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MAN1B1 encodes an enzyme belonging to the glycosyl hydrolase 47 family. Additionally we are shipping MAN1B1 Antibodies (16) and many more products for this protein.
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This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.
mannosidase, alpha, class 1B, member 1
, alpha 1,2-mannosidase
, ER alpha 1,2-mannosidase
, Man9GlcNAc2-specific processing alpha-mannosidase
, endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
, endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1
, ER alpha-1,2-mannosidase
, ER mannosidase 1
, man9GlcNAc2-specific-processing alpha-mannosidase