anti-Metastasis Suppressor 1 (MTSS1) Antibodies

May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.. Additionally we are shipping MTSS1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MTSS1 9788 O43312
MTSS1 211401 Q8R1S4
MTSS1 362918  
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Top anti-MTSS1 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to MTSS1 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] MTSS1 monoclonal antibody (M01), clone 2G9. Western Blot analysis of MTSS1 expression in human pancreas. 50 μg Log in to see 11 to 12 Days
$348.04
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: MTSS1 Sample Type: 721_B Whole Cell lysates Antibody Dilution: 1.0ug/ml  MTSS1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with MTSS1 antibody ABIN290367 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-MTSS1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse testicular lysate probed with Rabbit Anti-MTSS1 Polyclonal Antibody (ABIN762056) at 1:300 overnight in 4 °C. Followed by conjugation to the secondary antibody  at 1:5000 90min in 37 °C 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 16 Days
$293.00
Details
Chicken Rabbit Un-conjugated WB 100 μg Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, WB Human MTSS1 Western blot (WB) 6674 100 μg Log in to see 14 to 16 Days
$218.90
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 12 to 14 Days
$673.48
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using MTSS1 antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details

Top referenced anti-MTSS1 Antibodies

  1. Human Monoclonal MTSS1 Primary Antibody for IHC (p), ELISA - ABIN3013366 : Parr, Jiang: Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer. in European journal of cancer (Oxford, England : 1990) 2009 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal MTSS1 Primary Antibody for IF (p), IHC (p) - ABIN762056 : Chen, Chen, Zhao, Yang, Imran, Xing: Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model. in Journal of cancer research and clinical oncology 2013 (PubMed)

More Antibodies against MTSS1 Interaction Partners

Human Metastasis Suppressor 1 (MTSS1) interaction partners

  1. MTSS1 is stabilized by the protein phosphatase activity of the tumor suppressor PTEN. Our data show that PTEN loss in PDAC cells results in both increased metastatic potential and decreased MTSS1 expression. Furthermore, we show that ectopic MTSS1 expression rescues this effect.

  2. These data suggested that miR-411 played as oncogene in the osteosarcoma partly by inhibiting the MTSS1 expression. .

  3. Missing in metastasis B, regulated by DNMT1, functions as a putative cancer suppressor in human lung giant-cell carcinoma.

  4. Data identify MTSS1 as a new Akt2-regulated gene, and point to suppression of MTSS1 as a key step in the metastasis-promoting effects of Akt2 in CRC cells.

  5. Data suggest that overexpression of MAEL, caused by gene amplification and/or decreased miR-186, has a critical oncogenic role in UCB pathogenesis by downregulation of MTSS1.

  6. Overexpression of MTSS1 in PDAC cell lines leads to a loss of migratory potential in vitro and an increase in overall survival in vivo. Data provide insight into an important role for MTSS1 in suppressing tumor cell invasion and migration driven by the tumor microenvironment.

  7. Overexpression of MTSS1 reduced BUCC cell proliferation, cell-cycle progression and colony formation, but had no influence on BUCC cell apoptosis.

  8. in contrast to MIM, which is a prototype of I-BAR proteins and does not contain an SH3 domain, IRTKS promoted serum-induced cell migration along with enhanced phosphorylation of mitogen activated kinases Erk1/2 and p38

  9. this study shows a previously unknown property of MIM that establishes the linkage of protein ubiquitylation with Rab-guided trafficking of CXCR4 in endocytic vesicles

  10. MTSS1 suppressed H1299 cell migration and invasion, and its expression level can be used as a new independent factor for determining the prognosis of non-small cell lung cancer.

  11. MTSS1 is a new authentic target of miR-96 in prostate carcinoma.

  12. Down-regulation of MTSS1 expression is associated with lymph node metastasis in Pancreatic Cancer.

  13. Low expression of Mtss1 is associated with Chronic myeloid leukemia.

  14. MTSS1 plays an essential inhibitory role in the development and progression of ovarian cancers

  15. human breast tumors data sets the MTSS1/p63 co-expression is a negative prognostic factor on patient survival, suggesting that the MTSS1/p63 axis might be functionally important to regulate breast tumor progression

  16. our findings suggest that MTSS1 might have a context-dependent function and could act as a tumor suppressor, which is pharmacologically targetable in AML patients.

  17. EGF induces microRNAs that target suppressors of cell migration: miR-15b targets MTSS1 in breast cancer.

  18. These results implicate that the role of MTSS1 suppresses cell migration and invasion by inhibiting expression of CTTN and as a prognosis biomarker in Glioblastomas

  19. Data shows that MTSS1 is highly expressed in non-small-cell lung carcinomas compared with non-neoplastic lung tissues and may serve as an independent prognostic factor.

  20. The absence of MIM led to PTPdelta-mediated activation of SRC.

Mouse (Murine) Metastasis Suppressor 1 (MTSS1) interaction partners

  1. In the Title.

  2. Mtss1 is a key linker between the actin cytoskeleton and the cell membrane, for the development and maintenance of a paradigmatic neuronal circuit, the cerebellar cortex.

  3. Study showed that MTSS1 regulates neurite outgrowth and dendritic arborization in primary neurons in vitro, possibly through a Rac1- and PIP-dependent pathway.

  4. role of MIM in the homeostasis of BM cells, including HSPCs, through modulation of the CXCR4/SDF-1 axis and interactions of BM leukocytes with their microenvironments.

  5. Identify the inverse-BAR (I-BAR) protein MIM/MTSS1 as a nucleator of dendritic spines. MIM accumulated to future spine initiation sites in a PIP2-dependent manner and deformed the plasma membrane outward into a proto-protrusion via its I-BAR domain.

  6. The data demonstrated for the first time an important role for missing-in-metastasis protein in B-cell development. There was a predisposition of missing-in-metastasis-null mice to develop diffuse large B lymphomas.

  7. MTSS1 might be involved in shaping neuronal membranes in vivo.

  8. endogenous MIM protein regulates globally the cell architecture and endocytosis that ultimately influence a variety of cellular behaviors, including cell polarity, motility, receptor signaling and membrane ruffling

  9. MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.

  10. Results suggest that MIM promotes ciliogenesis by antagonizing Src-dependent phosphorylation of Cortactin and describe a mechanism linking regulation of the actin cytoskeleton with ciliogenesis and Shh signaling during tissue regeneration.

  11. tissue-specific regulator of cytoskeletal dynamics that interacts with ATP-actin monomers through its C-terminal WH2 domain

  12. Hedgehog-responsive gene MIM cooperates with receptor protein tyrosine phosphatase-delta to induce cytoskeletal remodeling.

  13. Mtss1 represents a novel signaling pathway from PDGF receptor to the actin cytoskeleton via Src-related kinases.

  14. The crystal structures of MIM's IMD and that of its WH2 bound to actin was determined.

  15. potential role of Mtss1 for cytoskeletal dynamics in developing and mature cerebellar neurons

Xenopus laevis Metastasis Suppressor 1 (MTSS1) interaction partners

  1. morphogenetic pathway involving Daam1 and MIM that transduces non-canonical Wnt signaling for the cytoskeletal changes and membrane dynamics required for vertebrate neural tube closure

MTSS1 Antigen Profile

Protein Summary

May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.

Gene names and symbols associated with MTSS1

  • MTSS1, I-BAR domain containing (MTSS1) antibody
  • transmembrane protein 65 (TMEM65) antibody
  • metastasis suppressor protein 1 (LOC100547471) antibody
  • MTSS1, I-BAR domain containing (mtss1) antibody
  • metastasis suppressor 1 (Mtss1) antibody
  • MTSS1, I-BAR domain containing (Mtss1) antibody
  • metastasis suppressor 1, gene 2 L homeolog (mtss1.2.L) antibody
  • 2310003N14Rik antibody
  • BC024131 antibody
  • D130001D01Rik antibody
  • mim antibody
  • mima antibody
  • mimb antibody
  • mKIAA0429 antibody
  • mtss1 antibody

Protein level used designations for MTSS1

metastasis suppressor 1 , metastasis suppressor protein 1 , metastasis suppressor protein 1-like , metastasis suppressor YGL-1 , missing in metastasis protein , actin monomer-binding protein

GENE ID SPECIES
711465 Macaca mulatta
100080535 Ornithorhynchus anatinus
100157797 Sus scrofa
100174755 Pongo abelii
100355361 Oryctolagus cuniculus
100410891 Callithrix jacchus
100467780 Ailuropoda melanoleuca
100547471 Meleagris gallopavo
100559325 Anolis carolinensis
100582996 Nomascus leucogenys
464381 Pan troglodytes
9788 Homo sapiens
482037 Canis lupus familiaris
100067482 Equus caballus
523498 Bos taurus
211401 Mus musculus
362918 Rattus norvegicus
420336 Gallus gallus
447209 Xenopus laevis
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