anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) Antibodies

involved in the O-acetylation of GD3 ganglioside sialic acid [RGD, Feb 2006].. Additionally we are shipping MFGE8 Kits (54) and MFGE8 Proteins (24) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MFGE8 4240 Q08431
MFGE8 17304 P21956
MFGE8 25277 P70490
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Top anti-MFGE8 Antibodies at antibodies-online.com

Showing 10 out of 187 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of MFG-E8 expression in A549 (A), NS-1 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Human Milk Fat Globule 1 antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue Lane 4: Recombinant Human MEGF8 Protein 1.25ng 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated FACS, WB HMFG Antibody (C-term) (ABIN656815) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the HMFG antibody detected the HMFG protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Mouse Hamster Un-conjugated IHC (fro), WB 0.1 mg Log in to see 6 to 8 Days
$368.50
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Rat Testis Tissue. 100 μg Log in to see 13 to 16 Days
$362.00
Details
Mouse Hamster Un-conjugated FACS, IP 0.1 mg Log in to see 6 to 8 Days
$368.50
Details
Human Mouse Un-conjugated CyTOF, FACS, WB Detection of MFG-E8 in Human Immature Dendritic Cells by Flow Cytometry. Human immature dendritic cells were stained with Mouse Anti-Human MFG-E8 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$297.85
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of Hela cells using  Lactadherin Antibody (C-term) Cat.-No AP52057PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of  Lactadherin Antibody (C-term) in Hela cell line lysates (35ug/lane). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Alexa Fluor 488 FACS Human immature dendritic cells were stained with Mouse Anti-Human MFG‑E8 Alexa Fluor® 488‑conjugated Monoclonal Antibody ( cells were fixed with Flow Cytometry Fixation Buffer (Catalog # <a class= 0.1 mg Log in to see 10 to 13 Days
$490.19
Details
Human Mouse Un-conjugated ICC, IHC, IHC (fro), IHC (p), WB Anti-MFGE8 / MFG-E8 antibody IHC staining of human placenta, trophoblast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN960988 concentration 10 ug/ml. Anti-MFGE8 / MFG-E8 antibody IHC of human placenta, trophoblast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details

MFGE8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MFGE8 Antibodies

  1. Human Monoclonal MFGE8 Primary Antibody for CyTOF, FACS - ABIN4899815 : Jinushi, Nakazaki, Carrasco, Draganov, Souders, Johnson, Mihm, Dranoff: Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment. in Cancer research 2008 (PubMed)
    Show all 2 Pubmed References

More Antibodies against MFGE8 Interaction Partners

Human Milk Fat Globule-EGF Factor 8 Protein (MFGE8) interaction partners

  1. This study showed for the first time that MFG-E8 expression is impaired in the endometrium of patients with endometriosis and infertility during the window of implantation.

  2. Our findings suggest that both MFGE8 and TGFbeta1 (show TGFB1 Antibodies) are agerelated inflammatory factors and are related to the degree of Atherosclerosis (AS). In conclusion, both MFGE8 and TGFbeta1 (show TGFB1 Antibodies) may serve as potential markers of the severity of AS

  3. Elevated serum MFG-E8 levels may be associated with cerebrovascular diseases or neuropsychiatric systemic lupus erythematosus.

  4. Circulating MFG-E8 levels are dramatically elevated in pregnancy, and are significantly higher in gestational diabetes mellitus than in normal pregnancy.

  5. MFG-E8 could be a potential novel prognostic marker for colorectal cancer (CRC (show CALR Antibodies)) and overexpression of MFG-E8 might be involved in lymph node metastasis and angiogenesis of CRC (show CALR Antibodies).

  6. MFG-E8 levels are elevated in T2D but suppressed by increased adipose tissues, thereby allowing inflammatory factors to rise to high levels. MFG-E8 may serve as a potential biomarker for obesity and T2D in the clinical setting

  7. These findings provide a better understanding of the molecular mechanism underlying colorectal cancer progression and suggest a predictive role for MFG-E8 in colorectal cancer metastasis and prognosis

  8. Levels of MFGE8 were reduced in cirrhotic liver tissue from patients compared with controls.

  9. an efficient purification method for production of non-aggregated, full-length MFG-E8.

  10. Reduced serum milk fat globule-epidermal growth factor (show EGF Antibodies) 8 (MFG-E8) concentrations are associated with an increased risk of microvascular complications in patients with type 2 diabetes.

Cow (Bovine) Milk Fat Globule-EGF Factor 8 Protein (MFGE8) interaction partners

  1. The vesicular environment provides optimal conditions for presentation and recognition of phosphatidylserine by lactadherin in a simple binding mechanism.

  2. lactophorin C-terminal fragment (LP16) and bovine milk fat globule membrane protein PAS6/7 strongly inhibited the replication of human rotavirus replication

  3. Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid-binding sites.

  4. The number of lactadherin binding sites increased proportionally to the phosphatidylserine content over a range 0-2% and less rapidly for higher phosphatidylserine content

  5. The crystal structure of the bovine lactadherin C2 domain (residues 1 to 158) at 2.4 A, was determined.

  6. angiogenic endothelial cells have phagocytic properties for lactadherin-opsonized large particles and apoptotic cells

Mouse (Murine) Milk Fat Globule-EGF Factor 8 Protein (MFGE8) interaction partners

  1. study suggests that LPS (show TLR4 Antibodies) represses MFG-E8 expression and disrupts enterocyte migration via a miR (show MLXIP Antibodies)-99b dependent mechanism.

  2. Mesenchymal stem cell-derived MFG-E8 might accelerate diabetic wound healing by promoting angiogenesis, the clearance of apoptotic cells, and the infiltration of M2 macrophages, and by suppressing inflammatory cytokines in wound area.

  3. MFG-E8 localized to the basal lamina of the mammary gland during involution. Basal MFG-E8 localization promoted integrin-dependent suppression of beta-casein (show CSN2 Antibodies) expression.

  4. MFG-E8 reduces neutrophil migration and neutrophil extracellular traps via downregulating surface CXCR2 (show CXCR2 Antibodies) expression in parallel with its role in the phagocytosis of apoptotic neutrophils.

  5. Mechanistically, ligation of alpha8beta1 by the milk protein Mfge8 reduces antral smooth muscle contractile force by preventing RhoA activation through a PTEN-dependent mechanism.

  6. MFG-E8 administration was associated with decreased inflammasome activation in the kidney. Adoptive transfer of MFG-E8-stimulated macrophages reduced activation of inflammasome and tissue damage. The protective role of MFG-E8 in ureteral obstruction kidney injury is mediated through anti-inflammatory macrophage reprogramming which results in decreased inflammasome activation, preventing severe tissue damage.

  7. characterization of the mechanisms by which macrophage derived MFG-E8 regulates wound inflammation; wound macrophage-derived MFG-E8 was recognized as a critical driver of wound angiogenesis

  8. MFG-E8 acts at two levels, by increasing VEGF (show VEGFA Antibodies) and ET-1 (show EDN1 Antibodies) expression in mesenchymal stromal cells (MSC (show MSC Antibodies)) and by enhancing M2 polarization of macrophages, to increase tumor angiogenesis.

  9. MFGE8 is an anti-fibrotic protein in mesenchymal stem cell secretomes that strongly inhibits TGFbeta (show TGFB1 Antibodies) signaling and reduces extracellular matrix deposition and liver fibrosis in mice.

  10. an efficient purification method for production of non-aggregated, full-length MFG-E8.

Pig (Porcine) Milk Fat Globule-EGF Factor 8 Protein (MFGE8) interaction partners

  1. The evidence suggests that lactadherin and the other F4-binding milk proteins, together with other defense components of milk, could play a role in protection of neonatal piglets against ETEC induced diarrhea.

MFGE8 Antigen Profile

Protein Summary

involved in the O-acetylation of GD3 ganglioside sialic acid

Gene names and symbols associated with MFGE8

  • milk fat globule-EGF factor 8 protein (mfge8) antibody
  • milk fat globule-EGF factor 8 protein (MFGE8) antibody
  • milk fat globule-EGF factor 8 protein b (mfge8b) antibody
  • milk fat globule-EGF factor 8 protein L homeolog (mfge8.L) antibody
  • milk fat globule-EGF factor 8 protein (Mfge8) antibody
  • AA408458 antibody
  • AGS antibody
  • AI325141 antibody
  • BA46 antibody
  • EDIL1 antibody
  • HMFG antibody
  • hP47 antibody
  • HsT19888 antibody
  • lactadherin antibody
  • MFG-E8 antibody
  • mfge8 antibody
  • Mfgm antibody
  • MFGME8 antibody
  • MFGMP-E8 antibody
  • MGC75581 antibody
  • MGC99228 antibody
  • MGC145109 antibody
  • OAcGD3S antibody
  • P47 antibody
  • SED1 antibody
  • SPAG10 antibody
  • zgc:154157 antibody

Protein level used designations for MFGE8

milk fat globule-EGF factor 8 protein , sperm-membrane associated protein P47 , O-acetyl disialoganglioside synthase , breast epithelial antigen BA46 , lactadherin , medin , sperm associated antigen 10 , sperm surface protein hP47 , BP47 , MFG-E8 , MFGM , MGP57/53 , PAS-6/PAS-7 glycoprotein , SED1 , components 15/16 , sperm surface protein SP47 , EGF/factor VIII , MP47 , milk fat globule glycoprotein , O-acetyl GD3 ganglioside synthase , O-acetyltransferase Milk fat glolbule membrane protein , O-acetyltransferase milk fat globule membrane protein , milk fat globule EGF factor 8 protein , pP47 protein

GENE ID SPECIES
395038 Xenopus (Silurana) tropicalis
415494 Gallus gallus
453631 Pan troglodytes
488730 Canis lupus familiaris
558580 Danio rerio
735060 Xenopus laevis
100033943 Equus caballus
100585952 Nomascus leucogenys
4240 Homo sapiens
281913 Bos taurus
17304 Mus musculus
25277 Rattus norvegicus
100861394 Capra hircus
397545 Sus scrofa
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