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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Additionally we are shipping MRPL40 Antibodies (37) and MRPL40 Proteins (4) and many more products for this protein.
Two-photon imaging of the genetically encoded fluorescent calcium indicator GCaMP6, expressed in presynaptic cytosol or mitochondria, showed that Mrpl40 haploinsufficiency deregulates STP (show SULT1A1 ELISA Kits) via impaired calcium extrusion from the mitochondrial matrix through the mitochondrial permeability transition pore.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
39S ribosomal protein L40, mitochondrial
, nuclear localization signal protein absent in velo-cardio-facial patients
, nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog
, mitochondrial ribosomal protein L22/24
, nuclear localization signal containing protein deleted in velocardiofacial syndrome
, nuclear localization signal deleted in velocardiofacial syndrome
, nuclear localization signal-containing protein deleted in velocardiofacial syndrome
, up-regulated in metastasis
, mitochondrial ribosomal protein L40
, mitochondrial ribosomal protein L40-like
, likely mitochondrial ribosomal protein MRPL40p