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Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Additionally we are shipping Mitochondrially Encoded NADH Dehydrogenase 2 Antibodies (21) and and many more products for this protein.
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gene variants not associated with total fertilization failure
The C5263T single-nucleotide mutation of the mitochondrial ND2 gene was observed in 2 young coronary heart disease (CHD) patients in the case group. The premature CHD of these 2 patients followed a pattern of maternal inheritance.
Data show no association between the mitochondrial 5178C/A polymorphism of NADH-dehydrogenase subunit 2 (ND2) gene with type-2 diabetes mellitus (T2DM), however, the polymorphism may affect the development of nephropathy and hypertension complications.
Study identified cancer-specific somatic variants in the ND2 and ND3 regions, and the presence of these mutated DNAs in the serum during the postoperative period accurately predicted poor prognoses in oral squamous cell carcinomas.
This study did not show a correlation between ARMS2, C3, MT-NDH2, and CFH alleles in the development of choroid neovascularization associated with ocular histoplasmosis.
The Mt5178 C/A genotype, which results in an amino acid polymorphism in NADH dehydrogenase subunit 2, may modify longitudinal changes in serum total cholesterol and high-density lipoprotein cholesterol levels in middle-aged Japanese men.
demethylation of the D-loop plays a key role in regulating ND2 expression during the initiation and/or progression of colorectal cancer.
For Mt5178C genotypic men, alcohol consumption may reduce the risk of hyper-LDL cholesterolemia
Novel mitochondrial DNA mutations in Parkinson's disease. we report novel homoplasmic base changes. We were unable to detect heteroplasmic base changes.
Mutation T4681C disturbs the mitochondrial electron transport complex I assembly pathway and leads to Leigh syndrome.
results suggest that ND2-237 Leu/Met polymorphism is associated with hypertension and that modification of hypertension risk is dependent on alcohol consumption in middle-aged Japanese men
mitochondrial MTND2 polymorphism may increase susceptibility to nucleoside reverse transcriptase inhibitors associated peripheral neuropathy
modifies the effects of coffee consumption on blood pressure or the risk of hypertension
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
NADH dehydrogenase subunit 2