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Involved in JNK signaling pathway (By similarity).. Additionally we are shipping MAPKBP1 Antibodies (19) and and many more products for this protein.
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We identified mutations in MAPKBP1 as a genetic cause of juvenile or late-onset and cilia-independent nephronophthisis.
JNKBP1 and NOD2 are co-expressed in the human intestinal epithelium and in immune cells recruited in the lamina propria, which suggests that JNKBP1 contributes to maintain NOD2-mediated intestinal immune homeostasis.
The Mapkbp1 protein could enhance the NF-kappaB (show NFKB1 Proteins) activation induced by MAP kinase (show MAPK1 Proteins) kinase kinase 7 and TNF Receptor-Associated Factor 2 (show TRAF2 Proteins) , and could promote TNF Receptor-Associated Factor 2 (show TRAF2 Proteins) polyubiquitination.
Involved in JNK signaling pathway (By similarity).
mitogen-activated protein kinase-binding protein 1
, mitogen-activated protein kinase binding protein 1
, JNK-binding protein 1
, mitogen activated protein kinase binding protein 1
, Jun N-terminal kinase binding protein 1
, Jun N-terminal kinase-binding protein 1