Mitogen-Activated Protein Kinase Kinase Kinase 10 Proteins (MAP3K10)

The protein encoded by MAP3K10 is a member of the serine/threonine kinase family. Additionally we are shipping MAP3K10 Antibodies (73) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAP3K10 308463  
MAP3K10 4294 Q02779
MAP3K10 269881  
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Top MAP3K10 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$340.00
Details
Insect Cells Human GST tag 5 μg Log in to see 11 to 12 Days
$516.00
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$346.62
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Insect Cells Human GST tag   10 μg Log in to see 3 to 4 Days
$310.00
Details
Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$318.85
Details

MAP3K10 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)
Human , , ,
,
Mouse (Murine) ,

More Proteins for Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10) Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10) interaction partners

  1. MST interaction with MOB1 is not essential for development and tissue growth control.

  2. We identified a direct target of miR-155 as MAP3K10 in osteosarcoma

  3. MAP3K4 is sufficiently mediate the TGFbeta-induced phosphorylation of p38 MAPK in MEFs and HaCaT cells.

  4. A novel and important role for MAP3K10 in the proliferation and chemoresistance of pancreatic ductal adenocarcinoma.

  5. This study showed that show that RUNX3 is a principal and evolutionarily conserved component of the MST pathway.

  6. Mechanism of MAP kinase activation by TNF requires Src-dependent activation of Vav, activation of Rac/Cdc42, and the engagement of the Rac/Cdc42 interaction site on MLK2 and 3.

  7. Data show that miR-181b contributed to proliferation of AML cells by targeting MLK2.

  8. MLK2 has a role in vesicle formation and endosome recycling by binding to clathrin

  9. demonstrate Alien-MLK2 interaction and also show that MLK2 is able to phosphorylate Alien; Alien, DAX-1 and thyroid hormone receptor mediated transcriptional silencing is strongly enhanced in the presence of active MLK2

  10. MLK2 and -3 are required for activation of JNK and p38 by ectopically expressed GCK

  11. Hippocalcin and MLK2 were colocalized in the halo of Lewy bodies in Parkinson disease patients, and neither protein was detected in normal pigmented neurons.

  12. Mixed lineage kinase phosphorylates transcription factor E47 and inhibits TrkB expression to link neuronal death and survival pathways

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10) interaction partners

  1. There is extensive functional redundancy between MLK1 and MLK2, and the other member of the family, MLK3, none of which are required for survival in mouse.

  2. Mixed lineage kinase phosphorylates transcription factor E47 and inhibits TrkB expression to link neuronal death and survival pathways

MAP3K10 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

Gene names and symbols associated with MAP3K10

  • mitogen-activated protein kinase kinase kinase 10 (MAP3K10)
  • mitogen activated protein kinase kinase kinase 10 (Map3k10)
  • mitogen-activated protein kinase kinase kinase 10 (Map3k10)
  • mitogen-activated protein kinase kinase kinase 10 L homeolog (map3k10.L)
  • BC028668 protein
  • BC046514 protein
  • MEKK10 protein
  • mlk2 protein
  • MST protein
  • xmlk2 protein

Protein level used designations for MAP3K10

mitogen-activated protein kinase kinase kinase 10 , mixed-lineage kinase 2 , MKN28 derived nonreceptor_type serine/threonine kinase , MKN28 kinase , mixed lineage kinase 2 , protein kinase MST , MKN28 derived nonreceptor_type , serine/threonine kinase

GENE ID SPECIES
700477 Macaca mulatta
100017495 Monodelphis domestica
100067981 Equus caballus
100343621 Oryctolagus cuniculus
308463 Rattus norvegicus
4294 Homo sapiens
269881 Mus musculus
484504 Canis lupus familiaris
100521453 Sus scrofa
781037 Bos taurus
398612 Xenopus laevis
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