anti-Mucin 16, Cell Surface Associated (MUC16) Antibodies

Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets (By similarity).. Additionally we are shipping MUC16 Kits (34) and MUC16 Proteins (25) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MUC16 94025 Q8WXI7
MUC16 73732  
MUC16 303554 Q501R9
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Top anti-MUC16 Antibodies at antibodies-online.com

Showing 10 out of 312 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of MUC16 staining in HuvEc cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MUC16 staining in human bladder cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Paraformaldehyde-fixed, paraffin embedded human cervical cancer, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with MUC16 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 100 μL Log in to see 3 to 7 Days
$318.45
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of HepG2 cells, using MUC16 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$417.45
Details
Human Mouse Un-conjugated IHC (fro), IHC (p)   0.5 mL Log in to see 6 to 8 Days
$313.50
Details
Human Mouse Un-conjugated IHC (p)   1 mL Log in to see 6 to 8 Days
$489.50
Details
Human Mouse Un-conjugated ELISA, IHC (p), WB Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (X75) [ABIN269634] - Analysis in in urinary bladder adenocarcinoma. Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (X75) [ABIN269634] - Analysis in antigen in serosal ovarian adenocarcinoma. 0.1 mg Log in to see 7 to 9 Days
$301.88
Details
Human Rabbit Un-conjugated IHC Immunohistochemistry of paraffin-embedded mouse lung using MUC16 antibody at dilution of 1:100 (x40 lens). Immunohistochemistry of paraffin-embedded human liver injury using MUC16 antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 16 Days
$334.02
Details
Human Rabbit Biotin IHC, ELISA, WB 100 μg Log in to see 13 to 16 Days
$346.00
Details

MUC16 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MUC16 Antibodies

  1. Human Polyclonal MUC16 Primary Antibody for IF (p), IHC (p) - ABIN724760 : Xie, Dong, Ren: Study on homogeneous competitive immune reaction by fluorescence correlation spectroscopy: using synthetic peptide as antigen. in Talanta 2009 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal MUC16 Primary Antibody for ELISA, IHC (p) - ABIN269634 : Heinzelmann-Schwarz, Gardiner-Garden, Henshall, Scurry, Scolyer, Davies, Heinzelmann, Kalish, Bali, Kench, Edwards, Vanden Bergh, Hacker, Sutherland, OBrien: Overexpression of the cell adhesion molecules DDR1, Claudin 3, and Ep-CAM in metaplastic ovarian epithelium and ovarian cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2004 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal MUC16 Primary Antibody for MA, ELISA - ABIN265646 : Cao, Partyka, McDonald, Brouhard, Hincapie, Brand, Hancock, Haab: Modulation of glycan detection on specific glycoproteins by lectin multimerization. in Analytical chemistry 2013 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal MUC16 Primary Antibody for ELISA, IF - ABIN1584127 : Motohara, Masuko, Ishimoto, Yae, Onishi, Muraguchi, Hirao, Matsuzaki, Tashiro, Katabuchi, Saya, Nagano: Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells. in Carcinogenesis 2011 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal MUC16 Primary Antibody for IHC (p), IHC - ABIN439508 : Labani-Motlagh, Israelsson, Ottander, Lundin, Nagaev, Nagaeva, Dehlin, Baranov, Mincheva-Nilsson: Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity. in Tumour biology 2016 (PubMed)

  6. Monoclonal MUC16 Primary Antibody for ELISA (Capture), ELISA - ABIN191166 : Jankovic, Tapuskovic: Molecular forms and microheterogeneity of the oligosaccharide chains of pregnancy-associated CA125 antigen. in Human reproduction (Oxford, England) 2005 (PubMed)

  7. Human Monoclonal MUC16 Primary Antibody for IHC (fro), IHC (p) - ABIN114577 : Leoncini, Maio, Mirabile, Baggi, Franchi: Glandular hamartoma of the larynx: report of a case. in Auris, nasus, larynx 2008 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal MUC16 Primary Antibody for ELISA - ABIN4257684 : Huhtinen, Suvitie, Hiissa, Junnila, Huvila, Kujari, Setälä, Härkki, Jalkanen, Fraser, Mäkinen, Auranen, Poutanen, Perheentupa: Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts. in British journal of cancer 2009 (PubMed)

  9. Human Polyclonal MUC16 Primary Antibody for IF (p) - ABIN724764 : Guo, Kenney, Muller, Adams, Rutledge, Romero, Murray-Krezan, Prekeris, Sklar, Hudson, Wandinger-Ness: R-ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis. in Molecular cancer therapeutics 2015 (PubMed)

More Antibodies against MUC16 Interaction Partners

Mouse (Murine) Mucin 16, Cell Surface Associated (MUC16) interaction partners

  1. Mesothelin (show MSLN Antibodies)/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.(

  2. MAMs MUC1 (show MUC1 Antibodies) and MUC16 contribute to the maintenance of immune homeostasis at the ocular surface by limiting TLR-mediated innate immune responses.

  3. MUC16 functions as an oncogene (show RAB1A Antibodies). The cytoplasmic tail is critical for MUC16 oncogenic properties.

  4. Data show that intraperitoneal injections of living CA 125 positive cells of OVCAR-3 cell line, and boosted by intravenous injection of the purified extracellular domain of CA 125 was found to have excellent immunoreactivity for CA 125 mAb production.

  5. the presence of MUC16 in murine ovarian cancer and in normal tissues

  6. Lack of any prominent abnormal phenotype in Muc16 knockout mice suggests that CA125/MUC16 is not required for normal development or reproduction

Human Mucin 16, Cell Surface Associated (MUC16) interaction partners

  1. knockdown of MUC16 significantly weakened the capabilities of cells for proliferation and migration

  2. In this platinum-resistant population, PD was typically detected earlier by imaging than by CA-125, irrespective of bevacizumab treatment. Disease status by CA-125 at the time of PD was not prognostic for overall survival. Regular radiologic assessment as well as symptom benefit assessment should be considered during PROC follow-up.

  3. Data characterized CA-125 kinetics and identified modeled kinetic parameters.

  4. these studies demonstrate that PPARgamma (show PPARG Antibodies) is an important modulator of MUC16 expression.

  5. These data point to a novel opportunity to enrich Abs at mucosal sites by targeting Abs to MUC16 through changes in Fc glycosylation, potentially blocking viral movement and sequestering the virus far from the epithelial border.

  6. The current study uncovers the contribution of oncogenic KRAS to serum marker CA125 production through a mechanism that involves the ERK (show EPHB2 Antibodies)/c-Myc (show MYC Antibodies) axis.

  7. Mesothelin (show MSLN Antibodies)/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.

  8. the loss of MUC16 and E-cadherin (show CDH1 Antibodies) expression resulted in the formation of more compact spheroids. In addition, our data describe an unusual link between E-cadherin (show CDH1 Antibodies) expression and less compact spheroids. Our data also emphasize the role of MUC16 and b1 integrin in Epithelial ovarian cancer (EOC) spheroid formation.

  9. Preoperative CA-125 can predict neither the progression-free nor overall survival for primary serous ovarian cancer patients.

  10. In pseudomyxoma peritonei CA125 was infrequently expressed by tumor cells, but in most of the cases adjacent nonneoplastic mesothelial cells.

MUC16 Antigen Profile

Protein Summary

Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets (By similarity).

Gene names and symbols associated with MUC16

  • mucin 16, cell surface associated (MUC16) antibody
  • mucin 16 (Muc16) antibody
  • NBR1, autophagy cargo receptor (Nbr1) antibody
  • mucin 16, cell surface associated (Muc16) antibody
  • mucin-16 (LOC476718) antibody
  • mucin-16 (LOC712735) antibody
  • 1110008I14Rik antibody
  • Ca125 antibody
  • Gm1480 antibody
  • MUC16 antibody
  • RGD1308422 antibody
  • RGD1311421 antibody

Protein level used designations for MUC16

CA-125 , CA125 ovarian cancer antigen , MUC-16 , mucin-16 , ovarian cancer-related tumor marker CA125 , ovarian carcinoma antigen CA125 , neighbor of BRCA1 gene 1 protein , next to BRCA1 gene 1 protein , next to the Brca1 , mucin 16, cell surface associated , mucin-16-like

GENE ID SPECIES
94025 Homo sapiens
73732 Mus musculus
303554 Rattus norvegicus
315451 Rattus norvegicus
476718 Canis lupus familiaris
712735 Macaca mulatta
744458 Pan troglodytes
769718 Gallus gallus
100023755 Monodelphis domestica
100517392 Sus scrofa
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