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Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. Additionally we are shipping Multimerin 1 Antibodies (62) and Multimerin 1 Kits (24) and many more products for this protein.
Showing 5 out of 9 products:
Human Multimerin 1 Protein expressed in Wheat germ - ABIN1311094
Satoh, Hirayama, Takano, Suzuki-Inoue, Sato, Ohta, Nakagomi, Ozaki: VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets. in Thrombosis journal 2014
C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes, have an altered bone phenotype.
Our data suggest that multimerin 1 supports platelet adhesive functions and thrombus formation, which will be important to verify by generating and testing selective multimerin 1 deficient mice.
VWF (show VWF Proteins) binding to MMRN1 was enhanced by shear exposure and ristocetin, and required VWF (show VWF Proteins) A1A2A3 region, specifically the A1 and A3 domains.
Lower levels of anti-elastin are related to CAD [ coronary artery disease ]
our studies identify MMRN1 expression as a novel biomarker that may refine acute myelogenous leukemia risk stratification.
multimerin 1 has a role in delivering and localizing factor V onto platelets prior to prothrombinase (show F10 Proteins) assembly
disulfide-linked complexes of multimerin and factor V in platelets could be important for modulating the function of platelet factor V and its delivery onto activated platelets
MMRN1 is a ligand for alphaIIbbeta3 and alphavbeta3
The MMRN1 binding site was located in Factor V.
Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin (show F2 Proteins) generation.
MMRN1 supported the adhesion of activated, but not resting, washed platelets over a wide range of shear rates
Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.
, elastin microfibril interface located protein 4
, elastin microfibril interfacer 4
, endothelial cell multimerin
, glycoprotein Ia*