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MSI2 encodes a protein containing two conserved tandem RNA recognition motifs. Additionally we are shipping MSI2 Antibodies (100) and MSI2 Proteins (5) and many more products for this protein.
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This line provides a valuable tool both for live imaging of the endogenous Msi2b at subcellular resolution and manipulation of Msi2b-expressing cells.
MSI2 expression was markedly increased in both PDAC cell lines and human PDAC specimens, and high MSI2 expression was associated with poor prognosis for PDAC. Forced MSI2 expression promoted PDAC proliferation, migration, and invasion in vitro and growth and metastasis in vivo, whereas knockdown of MSI2 expression did the opposite. Dysregulated KLF4 (show KLF4 ELISA Kits)/MSI2 signaling promotes PDAC progression and metastasis.
MSI1 (show MSI1 ELISA Kits) and MSI2 bind and regulate the mRNA stability and translation of proteins operating in essential oncogenic signaling pathways..This review provides a current overview of Musashi (show MSI1 ELISA Kits) as a cancer driver and novel therapeutic target.
High MSI2 expression is associated with esophageal squamous cell carcinoma.
High Musashi2 expression is associated with pancreatic cancer.
MSI2 regulates myeloid leukemia (show BCL11A ELISA Kits) stem cells gene expression.
these findings provide evidence that DBC2 suppresses tumorigenesis in breast cancer by ubiquitinating MSI2.
Differential methylation of the MSI2 gene (chr17:55484635) in blood and islet cells is strongly related to hyperglycemia.
our findings identified a novel regulatory mechanism of MSI2 as an upstream regulator of ESR1 (show ESR1 ELISA Kits) and revealed the clinical relevance of the RNA-binding protein (show PTBP1 ELISA Kits) MSI2 in breast cancer.
MSI2 might play a crucial role in sustaining stemness and chemoresistance of liver cancer stem cells in LIN28A (show LIN28A ELISA Kits)-dependent manner in hepatocellular carcinoma.
MSI2 and FLT3 (show FLT3 ELISA Kits) are significantly co-regulated in human AML (show RUNX1 ELISA Kits)
Absence of Musashi2 in osteoclast precursors promotes apoptosis and inhibits RANKL (show TNFSF11 ELISA Kits)-induced NF-kappaB (show NFKB1 ELISA Kits) activation, which is essential for osteoclast survival.
Msi2 primarily recognizes mRNA 3'UTRs at sites enriched in multiple copies of UAG motifs in epithelial progenitor cells.
Msi (show EBP ELISA Kits) proteins are dispensable for normal homeostasis and self-renewal of the active intestinal stem cell.
our findings reveal the importance of Msi2 in suppressing hair regeneration and maintaining hair follicle stem cells quiescence
studies highlight Msi (show EBP ELISA Kits) reporters as a unique tool to identify therapy resistance, and define Msi (show EBP ELISA Kits) signalling as a central regulator of pancreatic cancer
MSI1 (show MSI1 ELISA Kits) and MSI2 display distinct expression profiles during mammalian folliculogenesis and that MSI2 is required for pre-antral follicle development
Through expression studies and utilizing a transgenic Msi1 (show MSI1 ELISA Kits) testis-specific (show AIF1 ELISA Kits) overexpression model, we have identified 2 unique RNA-binding targets of MSI1 (show MSI1 ELISA Kits) in spermatogonia, Msi2 and Erh (show ERH ELISA Kits), and have demonstrated a role for MSI1 (show MSI1 ELISA Kits) in translational regulation.
Msi (show EBP ELISA Kits) proteins contribute to an epithelial gene expression program in neural and mammary cell types.
Msi2 is an important regulator of the hematopoietic stem cell (HSC) translatome and balances HSC homeostasis and lineage bias.
Ectopic expression of Musashi 2 isoform 1, but not isoform 2, enhanced the cloning efficiency of embryonic stem cells, but both isoforms were required for the self-renewal of embryonic stem cells.
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Two transcript variants encoding distinct isoforms have been identified for this gene.
musashi homolog 2 (Drosophila)
, musashi homolog 2
, musashi 2
, RNA-binding protein Musashi homolog 2
, Musashi homolog 2