Myocyte Enhancer Factor 2D (MEF2D) ELISA Kits

MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Additionally we are shipping MEF2D Antibodies (139) and MEF2D Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MEF2D 4209 Q14814
MEF2D 17261  
MEF2D 81518 O89038
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More ELISA Kits for MEF2D Interaction Partners

Human Myocyte Enhancer Factor 2D (MEF2D) interaction partners

  1. MEF2d mRNA level is up-regulated in both sporadic and SOD1 + ALS patients.

  2. MEF2D might be a potential biomarker during chronic inflammation-lung cancer transition, predicting the risk of lung cancer among patients with chronic respiratory diseases.

  3. HIF-1alpha (show HIF1A ELISA Kits) transactivates MEF2D expression by binding to the MEF2D gene promoter to induce angiogenesis in colorectal tumors.

  4. MEF2D directly regulated transcription of the epithelial-mesenchymal transition driver gene ZEB1 (show ZEB1 ELISA Kits) and facilitated histone acetylation at the ZEB1 (show ZEB1 ELISA Kits) promoter in colorectal cancer cells

  5. MEF2D-BCL9 (show BCL9 ELISA Kits)-positive patients had B-cell precursor immunophenotype and were characterized as being older in age, being resistant to chemotherapy, having very early relapse, and having leukemic blasts that mimic morphologically mature B-cell leukemia with markedly high expression of HDAC9 (show HDAC9 ELISA Kits).

  6. These results suggest that PPARgamma (show PPARG ELISA Kits) may exert its antiproliferative effects by negatively regulating the MEF2D in CM cells, which through upregulation of miR (show MLXIP ELISA Kits)-122, and PPARgamma (show PPARG ELISA Kits)/miR (show MLXIP ELISA Kits)-122/MEF2D signaling pathway may be a novel target for treatment of CM.

  7. MEF2D overexpression participated in the growth of lung cancers and its aberrant expression may result from the reduction of tumor suppressor miR (show MLXIP ELISA Kits)-218.

  8. MEF2D is a direct target of miR (show MLXIP ELISA Kits)-19.

  9. We found that in malignant glioma, there is an aberrantly high expression of MEF2D, which leads to poor prognosis of malignant glioma. The downregulation of MEF2D suppresses the proliferation of malignant glioma cell lines by inducing delay of S and G2/M phases of cell cycle and promoting apoptosis.

  10. MEF2D regulates IGF-1 (show IGF1 ELISA Kits)-induced proliferation and apoptosis in CM development, indicating IGF-1 (show IGF1 ELISA Kits)-MEF2D pathway may be a useful target for treatment.

Mouse (Murine) Myocyte Enhancer Factor 2D (MEF2D) interaction partners

  1. These findings uncover a novel role for Mef2c (show MEF2C ELISA Kits)/d in coordinating the transcriptional network that promotes early B-cell development.

  2. This study identifies MEF2D as a critical regulator of IL-10 (show IL10 ELISA Kits) gene expression that negatively controls microglia inflammation response and prevents inflammation-mediated cytotoxicity.

  3. Mef2d is essential for the maturation and integrity of retinal photoreceptor and bipolar cells

  4. miR (show MLXIP ELISA Kits)-103 worked through activating AKT (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) signal pathway and impairing target gene MEF2D.

  5. These findings demonstrate that broadly expressed TFs acquire specific functions through competitive recruitment to enhancers by tissue-specific Mef2d and through selective activation of these enhancers to regulate tissue-specific genes.

  6. Whereas MEF2A (show MEF2A ELISA Kits) is absolutely required for proper myoblast differentiation, MEF2B (show MEF2B ELISA Kits), -C, and -D were found to be dispensable for this process.

  7. A role for endogenous MEF2 (show MEF2C ELISA Kits) factors exclusively in hormone/Fsk/cAMP-induced Nr4a1 (show NR4A1 ELISA Kits) gene expression in mouse MA-10 Leydig cells.

  8. Oxidation of survival factor MEF2D inhibits its function, underlies oxidative stress-induced (show SQSTM1 ELISA Kits) neurotoxicity, and may be a part of the Parkinson disease pathogenic process.

  9. Results demonstrate that coordinated alternative splicing by a single RNA binding protein modulates transcription (Mef2d) and cell signaling (Rock2 (show ROCK2 ELISA Kits)) programs to drive tissue-specific functions (cell fusion) to promote a developmental transition.

  10. We found that Parkinson's disease -associated neurotoxins destabilize MEF2D mRNA and reduce its level in vitro and in vivo.

Cow (Bovine) Myocyte Enhancer Factor 2D (MEF2D) interaction partners

  1. Expression analysis showed that the MEF2D polymorphisms were highly correlated with MEF2D mRNA and protein levels in the longissimus dorsi muscle of Polish Holstein-Friesian bulls carrying the three different combined genotypes.

MEF2D Antigen Profile

Antigen Summary

This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MEF2D

  • myocyte enhancer factor 2D (mef2d) antibody
  • myocyte enhancer factor 2D (MEF2D) antibody
  • MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) (MEF2D) antibody
  • myocyte enhancer factor 2D (Mef2d) antibody
  • C80750 antibody
  • MGC145245 antibody
  • sl-1 antibody
  • sl1 antibody
  • XMEF2D antibody

Protein level used designations for MEF2D

myocyte enhancer factor 2D , MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) , myocyte-specific enhancer factor 2D-like , MADS box transcription enhancer factor 2, polypeptide D , myocyte-specific enhancer factor 2D

780389 Xenopus (Silurana) tropicalis
100023326 Monodelphis domestica
100406906 Callithrix jacchus
100459204 Pongo abelii
769067 Gallus gallus
4209 Homo sapiens
17261 Mus musculus
81518 Rattus norvegicus
490413 Canis lupus familiaris
100156714 Sus scrofa
100336730 Bos taurus
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