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NOP14 plays a role in the processing of the pre-18S rRNA and small ribosomal subunit assembly (Liu and Thiele, 2001 [PubMed 11694595]).[supplied by OMIM, Jun 2009]..
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Targeting NOP14 allows for effective suppression of tumor invasion in a mutp53-dependent manner, implicating NOP14 inhibition as a potential approach for attenuating metastasis in p53 (show TP53 Antibodies)-mutant tumors
NOP14 suppresses breast cancer progression by inhibiting NRIP1 (show NRIP1 Antibodies)/Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.
our study provides new evidence for NOP14 in regulating PC cell proliferation and migration, and may provide new insights for clinical diagnosis and therapy.
NOP14 plays a role in the processing of the pre-18S rRNA and small ribosomal subunit assembly (Liu and Thiele, 2001
, NOP14 nucleolar protein homolog
, nucleolar complex protein 14
, nucleolar protein 14
, nucleolar protein 14 homolog
, probable nucleolar complex protein 14