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The protein encoded by NPPC is proteolytically processed to form a secreted hormone of the natriuretic peptide family. Additionally we are shipping Natriuretic Peptide Precursor C Kits (4) and many more products for this protein.
Showing 10 out of 17 products:
C-type natriuretic peptide (CNP)administration significantly decreased the secretion and expression of MMP-2 (show MMP2 Antibodies) and MMP-9 (show MMP9 Antibodies) in the cultured mesangial cells ; (2) the secretion and expression of TIMP-1 (show TIMP1 Antibodies) progressively elevated after treatment with CNP (show CNP Antibodies) for 24 and 48 h, whereas declined at later time point; (3) CNP (show CNP Antibodies) expression was negatively correlated with MMP-2 (show MMP2 Antibodies) and MMP-9 (show MMP9 Antibodies) expression.
CNP (show CNP Antibodies) level in pericardial fluid is a more sensitive marker of LV dysfunction than CNP (show CNP Antibodies) levels in plasma in coronary artery disease patients undergoing coronary artery bypass grafting.
Data suggest mutations in NPR2 (show NPRL2 Antibodies) in patients with skeletal overgrowth alter conformation: A488P/R655C missense mutations yield conformation mimicking allosterically activated NPR2 (show NPRL2 Antibodies); A488P mutation sets phosphorylation as requirement for CNP (show CNP Antibodies)-dependent activation; R655C mutation abrogates need for phosphorylation; ATP analog inhibits mutants. (NPR2 (show NPRL2 Antibodies) = atrial natriuretic factor (show NPPA Antibodies) receptor B; CNP (show CNP Antibodies) = C-type natriuretic peptide)
CNP (show CNP Antibodies) may play a more important role than BNP (show BNC2 Antibodies) and ANP (show NPPA Antibodies) related peptides, as risk marker of obesity
CNP (show CNP Antibodies) and FGF-23 (show FGF23 Antibodies) act through a close or reciprocal pathway and are in agreement with recent studies demonstrating a down-regulatory role of the mitogen-activated protein kinase (show MAPK1 Antibodies) activity by CNP (show CNP Antibodies)
CNP (show CNP Antibodies)/NPR-B (show NPR2 Antibodies) can affect sperm motility and acrosome reaction, thus regulating the reproductive function of males
CNP (show CNP Antibodies) levels rose after paroxysmal supraventricular tachycardia and continued to rise after the termination.
examined whether CNP reduces hyaluronan production and export via members of the multidrug resistance protein (MRP) and diminishes pro-inflammatory effects in chondrocytes
Plasma CNP (show CNP Antibodies) might serve as a useful predictor for the therapeutic efficacy of metoprolol on postural tachycardia syndrome in children.
CNP (show CNP Antibodies)/proCNP could be new markers in human prostate cancer
CNP and BNP (show BNC2 Antibodies) serve as oocyte maturation inhibitor to inhibit oocyte maturation in mammals.
The first intron in the CNP sequence does not contain any additional enhancer-binding sites. However, the signal sequence is indispensable for secretion of CNP and its appropriate physiological function.
Inhibition of restenosis without compromising reendothelialization makes use of gene transfer into endothelial cells and muscle, smooth, vascular cells by administration of CNP.
Regional differences in BNP (show BNC2 Antibodies) and CNP expression were observed in myocardium with sustained left ventricular dyssynchronous contraction.
Data suggest natriuretic peptide precursor C (NPPC) can regulate oogenesis/gap junction mediated communication between oocytes and cumulus cells; here, NPPC is used in non-pharmacological coordination of meiotic prophase in vitro oocyte maturation.
E2-ERs system was functional in maintaining oocyte meiotic arrest by regulating the expression of natriuretic peptide C and natriuretic peptide receptor 2 (NPPC/NPR2 (show NPRL2 Antibodies))
CNP (show CNP Antibodies) activates bone turnover and remodeling in vivo and possibly accelerates fracture healing in a mouse model.
The up-to-day world-wide data about the structure, distribution, and physiological effects of the most poorly known among the natriuretic peptides--the C-type (CNP (show CNP Antibodies))--are summarized in the review.
Connexin mimetics directed against connexin-43 (Cx43 (show GJA1 Antibodies) CMP (show MATN1 Antibodies)) overcame NPPC-mediated meiotic arrest in both isolated cumulus oocyte complexes and antral follicles.
CNP (show CNP Antibodies)/NPR-C (show NPR3 Antibodies) pathway has potential as a disease-modifying therapeutic target for cardiovascular disorders
Data indicate an important, previously neglected, role of NEP (show MME Antibodies) for regulation of luminal factors in the epididymis and suggest a novel role for CNP (show CNP Antibodies)/guanylyl cyclase B in the epididymal epithelium
CNP (show CNP Antibodies) overexpression in chondrocytes can prevent endochondral growth delay and protect against cartilage damage in a mouse model of inflammatory arthritis.
Data suggest that intracerebroventricular administration of C-type natriuretic peptide (CNP-22 or CNP (show CNP Antibodies)-53) has anorexigenic effect on hypothalamic neurons via activation of melanocortin/melanocortin receptor signal transduction.
CNP (show CNP Antibodies)/NPR2 (show NPRL2 Antibodies) signaling is essential for oocyte meiotic arrest in early antral follicles and activated LH/amphiregulin (show AREG Antibodies)/EGFR (show EGFR Antibodies) signaling pathway suppresses this signal by downregulating Nppc expression.
we show that CNP (show CNP Antibodies) plays important region-specific roles in the GI tract of mice.
The protein encoded by this gene is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The encoded hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic.
C-type natriuretic peptide
, natriuretic peptide precursor C
, natriuretic peptide precursor type C
, C-type natriuretic peptide 3