anti-Nei Like 3 (E. Coli) (NEIL3) Antibodies

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family.

list all antibodies Gene Name GeneID UniProt
NEIL3 55247 Q8TAT5
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Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB   100 μg Log in to see 11 to 16 Days
Human Rabbit Un-conjugated WB   100 μL Log in to see 11 to 16 Days
Human Rabbit Un-conjugated   50 μL Log in to see 11 to 16 Days

NEIL3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)

More Antibodies against Nei Like 3 (E. Coli) Interaction Partners

Human Nei Like 3 (E. Coli) (NEIL3) interaction partners

  1. NEIL3-dependent modulation of DNA methylation (show HELLS Antibodies) regulates cardiac fibroblast proliferation and thereby affects extracellular matrix modulation after myocardial infarction.

  2. Data indicate that DNA glycosylases MYH (show MUTYH Antibodies), UNG2 (show CCNO Antibodies), MPG (show MPG Antibodies), NTH1, NEIL1 (show NEIL1 Antibodies), 2 and 3 on nascent DNA.

  3. These findings demonstrate that deficiency in NEIL3 is associated with increased lymphocyte apoptosis, autoantibodies, and predisposition to autoimmunity.

  4. SNPs in NEIL3 are associated with impulsivity in Native American sample.

  5. Single nucleotide polymorphism (SNP) rs142310826 near the NEIL3 gene showed a genome-wide significant interaction with caffeine consumption .There was no gender difference for this interaction (P = 0.64 for heterogeneity). NEIL3, a gene belonging to the base excision DNA repair pathway, encodes a DNA glycosylase that recognizes and removes lesions produced by oxidative stress.

  6. The abnormal expressions of NEIL1 (show NEIL1 Antibodies), NEIL2 (show NEIL2 Antibodies), and NEIL3 are involved in cancer through their association with the somatic mutation load.

  7. NEIL3 rs12645561 SNP TT genotype was associated with increased risk of myocardial infarction.

  8. Polymorphisms within FLT3 (show FLT3 Antibodies), EGFR (show EGFR Antibodies), NEIL3, and ALOX5 (show ALOX5 Antibodies) may contribute to the occurrence of GBM.

  9. Results show that the base excision and strand incision activities of NEIL3 exhibited a non-concerted action, indicating that NEIL3 mainly operates as a monofunctional DNA glycosylase.

  10. one role for Neil3 and NEIL1 (show NEIL1 Antibodies) is to repair DNA base damages in telomeres in vivo and that Neil3 and Neil1 (show NEIL1 Antibodies) may function in quadruplex-mediated cellular events, such as gene regulation via removal of damaged bases from quadruplex DNA.

Nei Like 3 (E. Coli) (NEIL3) Antigen Profile

Protein Summary

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002

Gene names and symbols associated with NEIL3

  • nei like DNA glycosylase 3 (NEIL3) antibody
  • FGP2 antibody
  • FPG2 antibody
  • hFPG2 antibody
  • hNEI3 antibody
  • NEI3 antibody

Protein level used designations for NEIL3

DNA glycosylase FPG2 , DNA glycosylase hFPG2 , DNA glycosylase/AP lyase Neil3 , endonuclease 8-like 3 , endonuclease VIII-like 3 , nei-like protein 3

55247 Homo sapiens
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