anti-Nemo-Like Kinase Antibodies

Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination.

Data Quality
  • 12
Type
  • 91
    Primary
Target
  • 91
Reactivity
  • 85
  • 50
  • 37
  • 3
  • 2
Application
  • 65
  • 39
  • 31
  • 26
  • 12
Host
  • 85
  • 6
Clonality
  • 88
  • 3
Clone
  • 1
Binding Specificity
  • 15
  • 14
  • 10
  • 9
  • 8
Conjugate
  • 35
  • 7
  • 7
  • 6
  • 5
Isotype
  • 69
  • 4
  • 2
  • 1
Format
  • 81
  • 2
Suggested next Filters
91 Products
ReactivityHuman
Application PLA, ELISA, WB
Order details Cat. No. ABIN526866
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse
Application ICC, IF, IHC (p), WB
Order details Cat. No. ABIN2856544
$509.08
100 μL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityHuman, Mouse
Application IHC (p), WB
Order details Cat. No. ABIN5534573
$550.00
400 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application IHC, WB
Order details Cat. No. ABIN3017553
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN928907
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityCow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Order details Cat. No. ABIN2786944
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse, Rat
Application ELISA, IHC, WB
Order details Cat. No. ABIN6263656
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IF, WB
Order details Cat. No. ABIN949348
$440.00
50 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application EIA, IHC (p), WB
Order details Cat. No. ABIN359699
$522.50
0.4 mL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application IHC (p), WB
Order details Cat. No. ABIN5534574
$550.00
400 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse, Rat
Application ELISA, WB
Order details Cat. No. ABIN6389256
$341.69
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse
Application ICC, IF, WB
Order details Cat. No. ABIN5622819
$534.64
100 μL
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN2692714
$247.82
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
ReactivityBat, Cow, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rat
Application WB
Order details Cat. No. ABIN6745669
$551.83
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN5516121
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
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Nemo-Like Kinase (NLK) Antigen Profile

Protein Summary

Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination. Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2. Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1. The NLK- SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing. The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs). Negative regulator of the canonical Wnt/beta-catenin signaling pathway. Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1. Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes. Negative regulator of the Notch signaling pathway. Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1. Negative regulator of the MYB family of transcription factors. Phosphorylation of MYB leads to its subsequent proteolysis while phosphorylation of MYBL1 and MYBL2 inhibits their interaction with the coactivator CREBBP. Other transcription factors may also be inhibited by direct phosphorylation of CREBBP itself. Acts downstream of IL6 and MAP3K7/TAK1 to phosphorylate STAT3, which is in turn required for activation of NLK by MAP3K7/TAK1 (By similarity).

Gene names and symbols associated with anti-Nemo-Like Kinase (NLK) Antibodies

  • glucose-6-phosphate isomerase (Gpi) antibody
  • nemo like kinase (NLK) antibody
  • nemo like kinase (Nlk) antibody
  • nemo-like kinase, type 1 (nlk1) antibody
  • nemo-like kinase L homeolog (nlk.L) antibody
  • nemo like kinase (nlk) antibody
  • Nemo-Like kinase (nemo-like) antibody
  • nemo-like kinase (nlk) antibody
  • AI194375 antibody
  • Amf antibody
  • Gpi1 antibody
  • nemo-like antibody
  • NLK antibody
  • nlk1 antibody
  • nlk2 antibody
  • nlkb antibody
  • RGD1561602 antibody
  • Xnlk antibody
  • zgc:111875 antibody

Protein level used designations for anti-Nemo-Like Kinase (NLK) Antibodies

NLK , PGI , PHI , autocrine motility factor , glucose phosphate isomerase , neuroleukin , phosphoglucose isomerase , phosphohexose isomerase , serine/threonine-protein kinase NLK , nemo-like kinase , serine/threonine protein kinase NLK , nemo like kinase b , nemo-like kinase 2 , Nemo-like kinase , Serine/threonine-protein kinase NLK , nemo like kinase , Nemo-Like kinase , serine/threonine-protein kinase NLK-like

GENE ID SPECIES
292804 Rattus norvegicus
51701 Homo sapiens
18099 Mus musculus
405892 Danio rerio
414522 Xenopus laevis
417669 Gallus gallus
445934 Takifugu rubripes
491160 Canis lupus familiaris
507204 Bos taurus
677693 Macaca mulatta
739132 Pan troglodytes
778685 Ciona intestinalis
100019356 Monodelphis domestica
100058876 Equus caballus
100144638 Xenopus (Silurana) tropicalis
100348930 Oryctolagus cuniculus
100414864 Callithrix jacchus
100469296 Ailuropoda melanoleuca
100511657 Sus scrofa
100560802 Anolis carolinensis
100593981 Nomascus leucogenys
497961 Rattus norvegicus
100729077 Cavia porcellus