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NRXN3 encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Additionally we are shipping Neurexin 3 Antibodies (52) and Neurexin 3 Kits (1) and many more products for this protein.
Showing 8 out of 17 products:
NRXN2 (show NRXN2 Proteins) may play a part in early cortical synaptogenesis, but NRXNs could have diverse roles in development including axon guidance, and intercellular communication between proliferating cells and/or migrating neurons.
The rare variants in NRXN3 were significantly associated with smoking status.
This study confirmed the genetic heterogeneity of cluster headache, suggesting that a novel rearrangement involving NRXN3 gene might be related to cluster headache in a subset of cases
The study showed that markers rs2217887 (NRXN3) showed weak associations.
a positive association between Neurexin 3 and controls in the Han Chinese population, and genetic evidence to support the susceptibility of DEACMP
Neurexin 3-alpha (NRXN3) is a synaptic cell-cell adhesion molecule (show PCDHB16 Proteins) involved in maintenance of neural connections (such as the maintenance of smoking behavior).
By age 7, common variations in FTO (show FTO Proteins), TMEM18 (show TMM18 Proteins) and NRXN3 influence the vulnerability to metabolic complications of sleep deprivation.
Our findings suggested that NRXN3 might represent a major susceptibility gene for schizophrenia
the study finds preliminary evidence for the association of NRXN3 with Borderline Personality Disorder phenotypes. The strongest association with positive screening for BPD was found for SNP rs10083466.
FoxQ1 (show FOXQ1 Proteins) promotes glioma cell proliferation and migration by down-regulation of NRXN3 expression.
Nrxn3 is responsible for the neuroligins (NLs)-induced assembly of GABAergic synapses in co-culture. Importantly, lentivirus-based expression of Nrxn3 containing exon 20 restores the reduced NLs-induced GABAergic contacts in the SLM2 E/E co-culture.
After pan-neurexin (show NRXN1 Proteins) deletions, we observed in these synapses severe but dramatically different synaptic phenotypes that ranged from major impairments in their distribution and function (climbing-fiber synapses) to large decreases in synapse numbers (parvalbumin (show PVALB Proteins)-positive synapses) and severe alterations in action potential-induced presynaptic Ca(2 (show CA2 Proteins)+) transients (somatostatin (show SST Proteins)-positive synapses).
Alternative splicing of presynaptic neurexin-3 controls postsynaptic AMPA (show GRIA3 Proteins) receptor trafficking, revealing an unanticipated alternative splicing mechanism for trans-synaptic regulation of synaptic strength and long-term plasticity.
N-terminal sequencing of cow neurexin III beta provides evidence for signal peptide
N-terminal sequencing of rat neurexin III alpha provides evidence for signal peptide
NRXN3 adhesion molecules may play an important role in the synaptic plasticity of neurons involved in the indirect pathways of basal ganglia
This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences.
, neurexin 3
, protocadherin alpha 12