Neuro-Oncological Ventral Antigen 2 Proteins (NOVA2)

May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Additionally we are shipping NOVA2 Antibodies (37) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NOVA2 4858 Q9UNW9
Mouse NOVA2 NOVA2 384569  
Rat NOVA2 NOVA2 292681  
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Top NOVA2 Proteins at

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available

NOVA2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Neuro-Oncological Ventral Antigen 2 (NOVA2) Interaction Partners

Human Neuro-Oncological Ventral Antigen 2 (NOVA2) interaction partners

  1. SCN1A (show SCN1A Proteins) polymorphism has a dramatic effect on the proportions of neonate and adult alternative transcripts of SCN1A (show SCN1A Proteins) in adult brain tissue and, the effect of the polymorphism also appears to be modified by Nova2 expression levels.

Mouse (Murine) Neuro-Oncological Ventral Antigen 2 (NOVA2) interaction partners

  1. NOVA2 uniquely regulates alternative splicing of a coordinate set of transcripts encoding key components in cortical, brainstem and spinal axon guidance/outgrowth pathways during neural differentiation, with severe functional consequences in vivo.

  2. Together, these results demonstrate that the production of DCC (show DCC Proteins) splice variants controlled by NOVA (show HNRNPK Proteins) has a crucial function during many stages of commissural neuron development.

  3. Phenotypic analysis of the NOVA (show HNRNPK Proteins)-deficient mice demonstrated increased adipose tissue thermogenesis and improved glycemia.

  4. These results reveal that Nova2 functions as an AS regulator in angiogenesis and is a novel member of the angioneurins family.

  5. integrative network revealed combinatorial regulation by Nova (show HNRNPK Proteins) and the neuronal splicing factor (show SLU7 Proteins) Fox, interplay between phosphorylation and splicing, and potential links to neurologic disease

  6. Nova2 regulates an RNA switch controlling the ability of Dab1 (show DAB1 Proteins) to mediate neuronal responsiveness to reelin (show RELN Proteins) signaling and neuronal migration, suggesting new links between splicing regulation, brain disease, and development.

  7. CLIP (cross-linking and immunoprecipitation) reveals Nova (show HNRNPK Proteins) coordinately regulates a biologically coherent set of RNAs encoding multiple components of the inhibitory synapse, an observation that may relate to the cause of abnormal motor inhibition in POMA

  8. Assays of splicing intermediates of Nova (show HNRNPK Proteins)-regulated transcripts in mouse brain revealed that Nova (show HNRNPK Proteins) preferentially regulates removal of introns harbouring (or closest to) YCAY clusters

  9. the neuron-specific splicing factor (show SLU7 Proteins) Nova (show HNRNPK Proteins) revealed extremely reproducible RNA-binding maps in multiple mouse brains

  10. Nova1/Nova2 double knockout mice are paralyzed and fail to cluster AChRs at the neuromuscular junction, and breeding them with transgenic mice constitutively expressing Z(+) agrin (show AGRN Proteins) in motor neurons rescued AChR clustering

NOVA2 Protein Profile

Protein Summary

May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA.

Gene names and symbols associated with NOVA2

  • NOVA alternative splicing regulator 2 (NOVA2)
  • neuro-oncological ventral antigen 2 (nova2)
  • neuro-oncological ventral antigen 2 (Nova2)
  • NOVA alternative splicing regulator 2 (Nova2)
  • neuro-oncological ventral antigen 2 L homeolog (nova2.L)
  • ANOVA protein
  • Gm1424 protein
  • MGC97842 protein
  • nova1 protein
  • nova1a protein
  • NOVA2 protein
  • NOVA3 protein

Protein level used designations for NOVA2

neuro-oncological ventral antigen 2 , neurological oncogenic ventral antigen protein , RNA-binding protein Nova-2 , astrocytic NOVA1-like RNA-binding protein , neuro-oncological ventral antigen 3 , neuro-oncological ventral antigen 1

468925 Pan troglodytes
595078 Xenopus (Silurana) tropicalis
100347797 Oryctolagus cuniculus
100512786 Sus scrofa
553201 Danio rerio
4858 Homo sapiens
612213 Canis lupus familiaris
537783 Bos taurus
384569 Mus musculus
292681 Rattus norvegicus
779126 Xenopus laevis
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