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Receptor for the neuromedin-U and neuromedin-S neuropeptides (By similarity). Additionally we are shipping Neuromedin U Receptor 1 Antibodies (51) and Neuromedin U Receptor 1 Proteins (5) and many more products for this protein.
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These results suggested that NMU can act directly on beta cells through NMUR1 in an autocrine or paracrine fashion to suppress insulin secretion. Collectively, our results highlight the crucial role of NMU in suppressing pancreatic insulin secretion, and may improve our understanding of glucose homeostasis.
Data show that deficiency of neuromedin receptors NMUR1 and NMUR2 had no impact on arthritis severity.
results suggested that NMU increases I(A) via activation of NMUR1 that couples sequentially to the downstream activities of Gbetagamma of the G(o) protein, PKA, and ERK
neuromedin-U receptor 1 inhibits L-type HVGCC via activation of NMUR1 and downstream G(betagamma), PI3K, and a novel PKC epsilon signaling pathway.
A study evaluating smooth muscle contraction in NMU1 receptor knockout mouse was used to determine which receptor subtype mediates the contractile responses generated by neuromedin in the mouse.[NMU1 receptor]
the pro-nociceptive effects of neuromedin U in mice appear to be mediated through NMUR2, not NMUR1
These data argues against a major role for Nmur1 in mediating the reported inflammatory functions of NmU.
Receptor for the neuromedin-U and neuromedin-S neuropeptides (By similarity).
neuromedin U receptor type 1
, neuromedin U receptor 1
, G protein-coupled receptor 66
, G-protein coupled receptor 66
, G-protein coupled receptor FM-3
, neuromedin-U receptor 1
, G protein-coupled receptor FM-3