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NEXN encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Additionally we are shipping Nexilin Kits (6) and Nexilin Proteins (6) and many more products for this protein.
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these results further emphasize the role of NEXN in dilated cardiomyopathy and suggest a novel role in endomyocardial fibroelastosis.
NEXN as a novel gene for ASD and its function to inhibit GATA4 established a critical regulation of an F-actin binding protein on a transcription factor in cardiac development
NELINinduced phenotypic transformation of human vascular smooth muscle cell was regulated via the RhoA/SRF signaling pathway.
This is the first study to identify NEXN as a novel coronary artery disease susceptibility gene with both genetic and functional evidence.
Nexilin is a component of the machinery that drives the formation of Listeria monocytogenes comet tails and enteropathogenic Escherichia coli pedestals.
the mutations in NEXN that we describe here may further expand the knowledge of Z-disc genes in the pathogenesis of HCM.
NELIN product is an F-actin associated protein and mediates cell motility
The findings of thi study on the role of nexilin in maintaining cardiac Z-disk integrity and on the workload dependence to cardiac Z-disk damage in nexilin-linked cardiomyopathy also might have implications for the treatment of NEXN-mutation carriers.
This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.
, F actin binding protein
, F-actin binding protein
, F-actin-binding protein
, nF actin binding protein
, nexilin alpha
, nexilin beta
, nexilin gamma