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The mouse ortholog of NRK encodes a protein kinase required for JNK activation.
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The results suggest that Nrk suppresses the excessive proliferation of mammary epithelial cells during pregnancy, and the impairment of this regulatory system leads to frequent occurrence of breast tumor in Nrk mutant mice.
regulates trophoblast proliferation and placental development by modulating AKT (show AKT1 ELISA Kits) phosphorylation
Nrk, an X-linked protein kinase in the germinal center kinase family, is required for placental development and fetoplacental induction of labor.
The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.
nik-related protein kinase
, Nik related kinase
, nik-related protein kinase-like
, NIK-like embryo-specific kinase
, nck-interacting kinase-like embryo specific kinase