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Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Additionally we are shipping NCAPD3 Antibodies (51) and and many more products for this protein.
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Condensin II(CAP-D3 and CAP-H2) and GAIT subunits associate with L1 RNA in a co-dependent manner, independent of IFN-gamma (show IFNG ELISA Kits). These findings suggest that cooperation between the Condensin II and GAIT complexes may facilitate a novel mechanism of L1 repression, thus contributing to the maintenance of genome stability in somatic cells
CAP-D3 down-regulates transcription of genes that encode amino acid transporters (SLC7A5 (show SLC7A5 ELISA Kits) and SLC3A2 (show SLC3A2 ELISA Kits)) to promote bacterial autophagy by colon epithelial cells.
The initial phase of chromosome condensation requires Cdk1 (show CDK1 ELISA Kits)-mediated phosphorylation of the CAP-D3 subunit of condensin II.
hCAP-D3 is a new biomarker for subtype-1 prostate tumors that improves prognostication.
We show here that protein phosphatase 2A (PP2A), which interacts with condensin II but not condensin I, plays an essential role in targeting condensin II to chromosomes.
The CAP-D3 subunit of the condensin II complex implicated in chromosome assembly and segeregation
Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003
non-SMC condensin II complex, subunit D3
, condensin II non-SMC subunit
, condensin-2 complex subunit D3
, condensin-2 complex subunit D3-like
, Jacobsen syndrome region 2