Nucleoporin 88kDa Proteins (NUP88)

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Additionally we are shipping Nucleoporin 88kDa Antibodies (53) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NUP88 19069 Q8CEC0
NUP88 113929 O08658
NUP88 4927 Q99567
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Top Nucleoporin 88kDa Proteins at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg 15 to 18 Days
$717.00
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Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg 15 to 18 Days
$720.00
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Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg 15 to 18 Days
$765.00
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Yeast Rat His tag   1 mg 60 to 71 Days
$4,170.83
Details

NUP88 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
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Rat (Rattus) ,
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Human ,
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More Proteins for Nucleoporin 88kDa (NUP88) Interaction Partners

Xenopus laevis Nucleoporin 88kDa (NUP88) interaction partners

  1. Data suggest that a pool of Nup88 on the nuclear side of the nuclear pore complex provides a novel, unexpected binding site for nuclear lamin A.

Mouse (Murine) Nucleoporin 88kDa (NUP88) interaction partners

  1. Nup88 is up-regulated in response to hypertonic stress and acts to retain TonEBP in the nucleus, activating transcription of critical osmoprotective genes.

  2. Nup88 regulates the activity of NF-kappaB at the level of nucleocytoplasmic transport.

Human Nucleoporin 88kDa (NUP88) interaction partners

  1. Here we report biallelic mutations in the nucleoporin NUP88 as a novel cause of lethal fetal akinesia deformation sequence (FADS) in two families. We demonstrate that NUP88 depletion affects rapsyn, a key regulator of the muscle nicotinic acetylcholine receptor at the neuromuscular junction.

  2. Study in HeLa cells revealed that Nup88 can affect the phosphorylation status of vimentin, which may contribute to the Nup88-dependent multinucleated phenotype through changing the organization of vimentin.

  3. Overexpression of the NUP88 is associated with cancer.

  4. Nup88 may be related to the occurrence of endometrial cancers and premalignant lesions

  5. These findings demonstrate that the NUP88-NUP98-RAE1-APC/CCDH1 axis contributes to aneuploidy

  6. Nup62 and Nup88 protein levels were significantly decreased upon knockdown of O-GlcNAc transferase.

  7. Serum Nup88 might be a candidate for a new biomarker implicated in the development and aggressiveness of colorectal cancer

  8. Nup88 mRNA was overexpressed in colorectal cancers and the overexpression was associated with cancer development and aggressiveness.

  9. Data suggest that a pool of Nup88 on the nuclear side of the nuclear pore complex provides a novel, unexpected binding site for nuclear lamin A.

  10. association found between myometrial invasion and Nup88 expression in endometrial carcinoma

  11. Gambogic acid exerts its anti-leukemia effects by regulating the expression and distribution of nucleoporin Nup88.

  12. proper expression of Nup88 is critical for preventing aneuploidy formation and tumorigenesis.

  13. High Nup88 mRNA expression levels correlated with ductal and tubular histology, nuclear grade 3, absence of hormone receptors, expression of c-erb-B2 oncogene and mutant p53 protein, high proliferation, DNA aneuploidy, and axillary node invasion.

  14. A monoclonal antibody for Nup88 in an experimental model for studying the role played by Nup88 during cell development and differentiation.

  15. the Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export

  16. Our data strongly indicate a dichotomous role for Nup88 in non-neoplastic and neoplastic conditions of the liver.

  17. The antitumor activity of deguelin was related to up-regulating the expression of Nup98 and down-regulating Nup88 protein.

  18. The formation of high molecular mass complexes containing importin-alpha, Nup153 and Nup88 is increased upon oxidant treatment.

  19. Nup88 is up-regulated in response to hypertonic stress and acts to retain TonEBP in the nucleus, activating transcription of critical osmoprotective genes.

  20. Nup88 is significantly overexpressed in high-grade CIN lesions and ISCC compared with normal ectocervical squamous epithelia and CIN1.

Nucleoporin 88kDa (NUP88) Protein Profile

Protein Summary

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias.

Gene names and symbols associated with Nucleoporin 88kDa Proteins (NUP88)

  • nucleoporin 88 (NUP88)
  • nucleoporin 88kDa S homeolog (nup88.S)
  • nucleoporin 88kDa L homeolog (nup88.L)
  • nucleoporin 88kDa (nup88)
  • nucleoporin 88 (Nup88)
  • Nup84 protein
  • nup88 protein
  • nup88A protein
  • nup88B protein
  • Prei2 protein

Protein level used designations for Nucleoporin 88kDa Proteins (NUP88)

nucleoporin 88kDa , nucleoporin Nup88B , nucleoporin Nup88A , nucleoporin 88 , nuclear pore complex protein Nup88 , nuclear pore complex protein Nup88-like , 88 kDa nucleoporin , preimplantation protein 2 , 88 kDa nuclear pore complex protein , nucleoporin Nup84 , nucleoporin Nup88 , karyoporin , nuclear pore complex protein 88

GENE ID SPECIES
100061117 Equus caballus
403363 Xenopus laevis
403364 Xenopus laevis
417501 Gallus gallus
549544 Xenopus (Silurana) tropicalis
607268 Canis lupus familiaris
711734 Macaca mulatta
748596 Pan troglodytes
100398342 Callithrix jacchus
100465869 Ailuropoda melanoleuca
100606497 Nomascus leucogenys
19069 Mus musculus
113929 Rattus norvegicus
4927 Homo sapiens
504786 Bos taurus
100725365 Cavia porcellus
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