anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) Antibodies

Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import (By similarity).. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ORAI3 93129 Q9BRQ5
ORAI3 269999 Q6P8G8
ORAI3 309000 Q6AXR8
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Top anti-ORAI3 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ORAI3 Antibody Titration: 1.0 ug/ml Positive Control: Placenta 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (fro), IF, WB 0.1 mg 6 to 8 Days
$478.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg 6 to 8 Days
$495.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IHC, IHC (p), WB Human Placenta (formalin-fixed, paraffin-embedded) stained with ORAI3 antibody ABIN351441 at 3 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-ORAI3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. 0.05 mg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Uterus (formalin-fixed, paraffin-embedded) stained with ORAI3 antibody ABIN337113 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-ORAI3 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC (fro), WB 0.1 mg 3 to 4 Days
$372.71
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, ELISA, WB 0.1 mg 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB ORAI3 Antibody (N-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ORAI3 antibody detected the ORAI3 protein (arrow). 400 μL 10 to 11 Days
$385.00
Details

Top referenced anti-ORAI3 Antibodies

  1. Human Polyclonal ORAI3 Primary Antibody for IF, WB - ABIN541602 : Lewis: Calcium signaling mechanisms in T lymphocytes. in Annual review of immunology 2001 (PubMed)
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  2. Human Polyclonal ORAI3 Primary Antibody for IF, WB - ABIN541607 : Navas-Martín, Weiss: Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development. in Journal of neurovirology 2004 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal ORAI3 Primary Antibody for IHC (fro), WB - ABIN2475965 : Weston, Lawrence: An educational strategy for teaching psychosocial pediatrics. in Southern medical journal 1975 (PubMed)
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  4. Human Polyclonal ORAI3 Primary Antibody for ICC, IF - ABIN4341607 : Dragoni, Laforenza, Bonetti, Reforgiato, Poletto, Lodola, Bottino, Guido, Rappa, Pareek, Tomasello, Guarrera, Cinelli, Aronica, Guerra, Barosi, Tanzi, Rosti, Moccia: Enhanced expression of Stim, Orai, and TRPC transcripts and proteins in endothelial progenitor cells isolated from patients with primary myelofibrosis. in PLoS ONE 2014 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal ORAI3 Primary Antibody for ICC, ELISA - ABIN1002948 : Soboloff, Spassova, Dziadek, Gill: Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication. in Biochimica et biophysica acta 2006 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal ORAI3 Primary Antibody for ICC, ELISA - ABIN1002947 : Mercer, Dehaven, Smyth, Wedel, Boyles, Bird, Putney: Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. in The Journal of biological chemistry 2006 (PubMed)
    Show all 3 Pubmed References

More Antibodies against ORAI3 Interaction Partners

Human ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) interaction partners

  1. miR18a and miR18b positively regulate Orai3 whereas miR34a represses Orai3 expression and function.

  2. discovered that it was not the N termini, but the loop2 regions connecting TM2 and TM3 of Orai1 and Orai3 that featured distinct properties, which explained the different, isoform-specific behavior of Orai N-truncation mutants.

  3. the conserved portion of the Orai N terminus is essential for STIM1, as it fine-tunes the open Orai channel gating, thereby establishing authentic CRAC channel activity.

  4. mRNA expression in differentiated keratinocytes increased with increasing age of donors, and the increase corresponded well to slower recovery of [Ca2+]i from hydraulic stress-induced elevation in keratinocytes of older donors

  5. ORAI1-3, are preferentially expressed in proximal tubular epithelial cells and downregulated in patients with diabetic nephropathy.

  6. These data suggest that Orai3 channel does not participate in the thapsigargin-revealed ER Ca(2+) leak but forms an ER Ca(2+) leak channel that is limiting the overloading with Ca(2+) of the ER store.

  7. results identified the ORAI-NOX2 feedback loop as a determinant of monocyte immune responses.

  8. Overall high Orai3/Orai1 ratios in human prostate epithelial cells and androgen-insensitive cancer cells contribute to their ROS resistance and thereby may have a share in making the prostate one of the most prominent cancer susceptible organs

  9. A channel chimera of Orai3 with the N terminus of Orai1 was able to couple local Ca(2+) entry to NFAT activation, identifying the N-terminal domain of Orai1 as central to Ca(2+) nanodomain-transcription coupling.

  10. Orai3 down-tunes efficient STIM1 gating when in a heteromeric complex with Orai1.

  11. The higher amplitude of store-operated Ca2+ entry was associated to the over-expression for Stim2, Orai2-3, and TRPC1 while Stim2 levels remained constant and Stim1, Orai1, Orai3, TRPC1 and TRPC4 proteins were over-expressed in primary myelofibrosis.

  12. Suggest disrupted dynamic equilibrium of channel-forming ORAI proteins as an oncogenic mechanism in prostate cancer.

  13. Orai3 constitutes a native store-operated calcium entry pathway in non small cell lung adenocarcinoma that controls cell proliferation and cell cycle progression, likely via Akt pathway.

  14. Orai1 and Orai3 proteins are more important than calcium influx to control cell proliferation.

  15. High ORAI3 expression is associated with breast cancer.

  16. data establish Orai3 as an ERalpha-regulated channel and a potential selective therapeutic target for ERalpha(+) breast cancers

  17. the N-terminal conserved region plays a multifaceted role in Orai3 current gating with distinct structural requirements for STIM1- and 2-APB-stimulated activation.

  18. With these data we show a new Ca(2)(+) entry pathway linked to the Ca(2)(+)/inositolphosphate second-messenger system in RPE cells which help to further understand regulatory pathways of agonists.

  19. Results provide strong evidence for a significant effect of Orai3 on breast cancer cell growth in vitro and show that this effect is associated with the induction of cell cycle and apoptosis resistance.

  20. there is a selective requirement for Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells

Mouse (Murine) ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) interaction partners

  1. results identified the ORAI-NOX2 feedback loop as a determinant of monocyte immune responses.

  2. VEGF signaling via arachidonic acid and arachidonic acid metabolism causes Orai3 to accumulate at the cell surface to mediate Ca(2+) entry and downstream endothelial cell remodeling.

ORAI3 Antigen Profile

Protein Summary

Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import (By similarity).

Gene names and symbols associated with ORAI3

  • ORAI calcium release-activated calcium modulator 3 (ORAI3) antibody
  • ORAI calcium release-activated calcium modulator 3 (Orai3) antibody
  • 9930124N15 antibody
  • BC061259 antibody
  • ORAI3 antibody
  • RGD1306538 antibody
  • Tmem142c antibody

Protein level used designations for ORAI3

protein orai-3 , ORAI calcium release-activated calcium modulator 3 , transmembrane protein 142C , calcium release-activated calcium channel 3 , calcium release-activated calcium modulator 3 protein

GENE ID SPECIES
515971 Bos taurus
607303 Canis lupus familiaris
93129 Homo sapiens
269999 Mus musculus
309000 Rattus norvegicus
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