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May function as a cellular signal transducer.. Additionally we are shipping Odz, Odd Oz/ten-M Homolog 3 (Drosophila) Antibodies (41) and and many more products for this protein.
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This report supports the association of TENM3 mutations with colobomatous microphthalmia and expands the phenotypic spectrum associated with mutations in this gene
Null mutation in ODZ3 causes autosomal recessive microphthalmia in humans.
Ipsilateral retinal axons in Ten-m3 knockout mice are mismapped as a consequence of early axonal guidance defects. The aberrant invasion of the ventral-most region of the dorsal lateral geniculate nucleus by ipsilateral retinal axons in Ten-m3 knockouts suggested changes in the expression of other axonal guidance molecules, particularly members of the EphA-ephrinA family.
Results demonstrate that Ten-m3 plays a key role in directing the formation of thalamostriatal circuitry, the first molecular candidate reported to regulate connectivity within this pathway
This study demonstrated that ipsilateral inputs to V1 are expanded and mismatched with respect to contralateral inputs in Ten-m3 knockout mice.
Ten-m3 plays a critical role in this process and is particularly important for the mapping of the ipsilateral retinocollicular pathway.
Ten_m3 regulates the alignment of ipsilateral and contralateral projections. It is expressed in a gradient in the developing visual pathway, which is consistently highest in regions that represent dorsal visual field
May function as a cellular signal transducer.
, odd Oz/Ten-m homolog 3
, odz, odd Oz/ten-m homolog 3
, protein Odd Oz/ten-m homolog 3
, odd Oz/ten-m homolog 3
, odd oz/ten-m3
, seizure resistant s334
, odz, odd Oz/ten-m homolog 1(Drosophila)
, odz, odd Oz/ten-m homolog 1 (Drosophila)