Ornithine Aminotransferase (OAT) ELISA Kits

OAT encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Additionally we are shipping OAT Antibodies (68) and OAT Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
OAT 18242 P29758
OAT 64313 P04182
OAT 4942 P04181
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Top OAT ELISA Kits at antibodies-online.com

Showing 4 out of 15 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.067 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$736.84
Details
Rat < 0.33 ng/mL 0.78 ng/mL - 50 ng/mL   96 Tests Log in to see 11 to 18 Days
$653.82
Details
Mouse
  96 Tests Log in to see 11 to 18 Days
$653.82
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Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

More ELISA Kits for OAT Interaction Partners

Mouse (Murine) Ornithine Aminotransferase (OAT) interaction partners

  1. The data highlight the importance of OAT in ornithine metabolism, especially in the liver, and suggest a post-transcriptional regulation of OAT by LPS in the liver.

  2. in female and castrated male mice devoided of testosterone, OAT gene is highly expressed and L-ornithine is converted into L-glutamate.

  3. In H4Flox liver, glutamine synthetase (GS), ornithine aminotransferase (OAT) and thyroid hormone-receptor beta1 (TRbeta1) were exclusively expressed in pericentral hepatocytes.

  4. Sexual dimorphism of Oat expression in the kidney was observed.

Human Ornithine Aminotransferase (OAT) interaction partners

  1. One novel homozygous missense mutation in OAT was identified and considered to be pathogenic in a patient with gyrate atrophy. The response for the vitamin B6 supplementation was positive.

  2. Study identifies differentially variable CpG sites in OAT gene displaying increased expression in patients with chronic obstructive pulmonary disease.

  3. OAT Val332-to-Met substitution identified in pyridoxine-responsive gyrate atrophy patients does not significantly affect the spectroscopic and kinetic properties of OAT, but during catalysis it makes the protein prone to convert into the apo-form, which undergoes unfolding and aggregation under physiological conditions.

  4. identified Arg217 as an important hot-spot at the dimer-dimer interface of hOAT and demonstrated that the artificial dimeric variant R217A exhibits spectroscopic properties, Tm values and catalytic features similar to those of the tetrameric species. This finding indicates that the catalytic unit of hOAT is the dimer.

  5. Sequencing of the gene for ornithine aminotransferase reveals a homozygous mutation in our patient (base exchange c.498C>A in Exon 4).

  6. Neurogenesis is inhibited by X-OAT during Xenopus embryonic development, but it is essential for Xenopus embryonic development. The Arg 180 and Leu 402 are crucial for these effects of the OAT molecule in development.

  7. Our report describes the first case of gyrate atrophy in the Korean population diagnosed by OAT gene analysis and treated with vitamin B6 dietary supplementation.

  8. We identified a novel frameshift mutation (p.K169DfsX10) in the OAT gene. While an early arginine-restricted dietary treatment suppressed the fundus changes

  9. Data suggest that other factors besides the specific ornithine aminotransferase (OAT) genotype modulate atrophy of choroid and retina (GA) phenotype in patients.

  10. OAT was a highly homologous and stable protein located in the mitochondria.

  11. Molecular analysis revealed a new deletion c.532_536delTGGGG (p.Trp178X) and a known mutation c.897C>G (p.Tyr299X) in the OAT gene.

  12. Fundus autofluorescence imaging can reveal the extent of neurosensory dysfunction in gyrate atrophy patients.

  13. analysis of ornithine aminotransferase substrate specificity

OAT Antigen Profile

Antigen Summary

This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.

Gene names and symbols associated with OAT

  • Ornithine aminotransferase precursor (Oat) antibody
  • ornithine aminotransferase, gene 1 (oat.1) antibody
  • ornithine aminotransferase (OAT) antibody
  • ornithine aminotransferase (Lbys_2951) antibody
  • ornithine aminotransferase (Riean_0998) antibody
  • ornithine aminotransferase (Ftrac_2019) antibody
  • ornithine aminotransferase (Celal_2605) antibody
  • ornithine aminotransferase (Deipr_1149) antibody
  • ornithine aminotransferase (Celly_0230) antibody
  • ornithine aminotransferase (Weevi_2065) antibody
  • ornithine aminotransferase (Fluta_4071) antibody
  • ornithine aminotransferase (Halhy_2848) antibody
  • ornithine aminotransferase (Theth_0565) antibody
  • ornithine aminotransferase (oat) antibody
  • ornithine aminotransferase (Oat) antibody
  • 151832_at antibody
  • AI194874 antibody
  • CG8782 antibody
  • Dmel\\CG8782 antibody
  • GACR antibody
  • HOGA antibody
  • OATASE antibody
  • OKT antibody
  • rOAT antibody

Protein level used designations for OAT

CG8782-PA , Oat-PA , ornithine aminotransferase , ornithine aminotransferase precursor , ornithine aminotransferase (gyrate atrophy) , ornithine aminotransferase, mitochondrial , ornithine--oxo-acid aminotransferase , gyrate atrophy , ornithine delta-aminotransferase , ornithine-oxo-acid aminotransferase

GENE ID SPECIES
40145 Drosophila melanogaster
379754 Xenopus laevis
450803 Pan troglodytes
477858 Canis lupus familiaris
9956831 Leadbetterella byssophila DSM 17132
10001754 Riemerella anatipestifer ATCC 11845 = DSM 15868
10012165 Marivirga tractuosa DSM 4126
10145026 Cellulophaga algicola DSM 14237
10256630 Deinococcus proteolyticus MRP
10262214 Cellulophaga lytica DSM 7489
10283330 Weeksella virosa DSM 16922
10399445 Fluviicola taffensis DSM 16823
10587022 Haliscomenobacter hydrossis DSM 1100
10885318 Thermotoga thermarum DSM 5069
100337582 Xenopus laevis
18242 Mus musculus
64313 Rattus norvegicus
4942 Homo sapiens
505323 Bos taurus
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