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It is unlikely that this protein has phospholipase A2 activity.. Additionally we are shipping OC90 Antibodies (19) and OC90 Proteins (4) and many more products for this protein.
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Our results suggest that Otoc1 may serve to nucleate calcium carbonate mineralization of aragonitic otoliths.(OTOC1 PROTEIN, DANIO RERIO)
calcium carbonate crystal growth data demonstrate that Otolin-1 and OC90 modulate in vitro calcite crystal morphology but neither protein is sufficient to produce the shape of otoconia
Report otoconin 90 is attached to a scaffold consisting of the hexagonal fibrillar meshwork, characteristic of otolin, in the otoconia.
In vivo, the presence of Oc90 in wildtype (wt) mice leads to an enrichment of Ca2 (show CA2 ELISA Kits)+ in the luminal matrices of the utricle and saccule, whereas absence of Oc90 in the null mice leads to drastically reduced matrix-Ca2 (show CA2 ELISA Kits)+.
Otolin 1 interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1 (show CBLN1 ELISA Kits) in the inner ear.
OC90 is a multifunctional molecule which facilitates calcite nucleation, inhibits crystal growth and induces changes in crystal morphology, which result in a shape characteristic of native otoconia.
Results show normal inner ear epithelial morphology but reduced acellular matrices, including otoconial, cupular and tectorial membranes, in Oc90 null mice, likely due to an absence of Oc90 and a profound reduction of otolin.
Otoconin-90 deletion in knockout mice leads to vestibular apparatus abnormalities and impairment of balance.
It is unlikely that this protein has phospholipase A2 activity.
, otoconin 90
, phospholipase A2
, PLA2-like otoconin
, phospholipase A2 homolog
, phospholipase A2-like like