Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) ELISA Kits

OLR1 encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. Additionally we are shipping OLR1 Antibodies (224) and OLR1 Proteins (29) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
OLR1 4973 P78380
OLR1 108078 Q9EQ09
OLR1 140914 O70156
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Top OLR1 ELISA Kits at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.057 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$700.00
Details
Rat 22.5 pg/mL 62.5 pg/mL - 4000 pg/mL 96 Tests Log in to see 13 to 16 Days
$760.00
Details
Mouse 19.5 pg/mL 78-5000 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$910.56
Details
Rabbit 24 pg/mL 78 pg/mL - 5000 pg/mL 96 Tests Log in to see 13 to 16 Days
$760.00
Details
Cow 13.2 pg/mL 31.25 pg/mL - 2000 pg/mL 96 Tests Log in to see 13 to 16 Days
$840.00
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Guinea Pig 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rhesus Monkey
  96 Tests Log in to see 31 to 41 Days
$734.80
Details

Top referenced OLR1 ELISA Kits

  1. Human OLR1 ELISA Kit for Sandwich ELISA - ABIN414847 : Zhao, Zhu, Luo, Lin, Chen: Circulating soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are associated with angiographic coronary lesion complexity in patients with coronary artery disease. in Clinical cardiology 2011 (PubMed)
    Show all 10 Pubmed References

  2. Mouse (Murine) OLR1 ELISA Kit for Sandwich ELISA - ABIN858317 : Takeda, Hirota, Teradaira, Takeda-Imoto, Watanabe, Toda, Aramaki: Cannabidiol-2',6'-dimethyl ether stimulates body weight gain in apolipoprotein E-deficient BALB/c. KOR/Stm Slc-Apoe(shl) mice. in The Journal of toxicological sciences 2016 (PubMed)

  3. Human OLR1 ELISA Kit for Sandwich ELISA - ABIN1672809 : Honjo, Sawamura, Hinagata, Nakamura, Sanada, Tanihara, Honda, Kiryu: Expression of LOX-1, an oxidized low-density lipoprotein receptor, in choroidal neovascularization. in Archives of ophthalmology (Chicago, Ill. : 1960) 2004 (PubMed)
    Show all 4 Pubmed References

  4. Rat (Rattus) OLR1 ELISA Kit for Sandwich ELISA - ABIN431424 : An, Zhang, Yu, Ma, Lu, Liu, Xiao: 27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells. in Neurotoxicology 2017 (PubMed)

  5. Human OLR1 ELISA Kit for Sandwich ELISA - ABIN456457 : Yang, Zhang, Zheng: Soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in synovial fluid are correlated with disease severity of knee osteoarthritis. in Clinical biochemistry 2011 (PubMed)

More ELISA Kits for OLR1 Interaction Partners

Rabbit Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. ox-LDL and LOX-1 increase due to subarachnoid hemorrhage and they may play a role in the pathogenesis of vasospasm.

  2. LOX and LOXL2 play an important role in wound healing after glaucoma filtration surgery. Targeting LOXL2 with an inhibitory monoclonal antibody (GS-607601) had a broader efficacy than targeting LOX, reducing angiogenesis and inflammation, and fibrosis.

  3. Angiotensin (1-7) inhibited LOX-1 expression and diminished Ang II-mediated inflammation in endothelial cells

  4. Elevated LOX-1 expression and inflammatory responses are induced in hypercholesterolemic rabbits by Chlamydia pneumoniae GroEL1 heat shock protein.

  5. Early treatment with fluvastatin had a crucial endothelial protective effect by down-regulating LOX-1 expression level in atherosclerotic arteries in early atherosclerosis.

  6. LOX-1 expression appears to be closely associated with tissue factor expression, apoptotic events and morphological vulnerability in atherosclerotic lesions

Human Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. Study showed that a high expression of LOX-1 was associated with poor prognosis in gastric cancer (GC) patients and TNM stage. LOX-1 was found to promote migration, invasion and epithelial-mesenchymal transition (EMT) of GC cells through activating PI3K/Akt/GSK3beta pathway.

  2. LOX-1(+) CD15(+) polymorphonuclear myeloid-derived suppressor cells were elevated in hepatocellular carcinoma patients and suppressed T cell proliferation through ROS/Arg I pathway induced by ER stress.

  3. High LOX-1 ligand activity as a risk factor for ischemic stroke.

  4. The analysis also revealed that OLR1 is not required for the transcriptional regulation induced by oxidized PAPC but interestingly, OLR1 knockdown affected expression of CNN2, HMRR, ITGB6 and KIF20A, all genes governing cell proliferation and motility.

  5. Data show that oxidized low density lipoprotein receptor 1 (LOX-1) is overexpressed in prostate cancer cells.

  6. L5-LDL, a naturally occurring mild oxidized LDL, induced G-CSF and GM-CSF production in human macrophages through LOX-1, ERK2, and NF-kappaB dependent pathways

  7. expression significantly higher in the arterial wall of epicardial coronary arteries compared to intramyocardial coronary arteries

  8. let7g exerts a LOX1independent antiaging effect on endothelial cells.

  9. high LOX-1 expression in pancreatic cancer tissues is indicative for the occurrence of lymph node metastases, high TNM stages and a poor prognosis.

  10. lincRNAp21 is a major mediator of oxLDLinduced apoptosis and expression of LOX1 in human vascular endothelial cells, and acts via activation of PKCdelta.

  11. this study shows that LOX-1 is involved in IL-1beta production and extracellular matrix breakdown in dental peri-implantitis

  12. Results showed that the scFv with N-terminal fusing peptides proteins demonstrated increased LOX-1-binding activity without decrease in stability. These findings will help increase the application efficacy of LOX-1 targeting scFv in LOX-1-based therapy

  13. The serum sLOX-1 level was higher in patients with large artery atherosclerotic stroke, and it was an independent predictor of functional outcome in patients with large artery atherosclerotic ischemic stroke.

  14. LOX-1 has a role in atherogenesis and tumorigenesis as a potential link in these diseases [review]

  15. the rs1050283 T allele of LOX-1 is strongly associated with an increased risk for atherosclerotic cerebral infarction in a Chinese population, which also affects levels of LOX-1 and sLOX-1

  16. data revealed that miR-let-7g exhibits anti-atherosclerotic activity, at least partially by targeting the LOX-1 signaling pathway.

  17. High LOX1 expression is associated with colorectal cancer.

  18. Increased LOX-1 expression in endothelial cells is potentially involved in the pathogenesis of sickle cell disease vasculopathy

  19. LOX-1 signalling and the crucial role of cytokines

  20. High OLR1 expression is associated with breast cancer.

Mouse (Murine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. The analysis also revealed that OLR1 is not required for the transcriptional regulation induced by oxidized PAPC but interestingly, OLR1 knockdown affected expression of CNN2, HMRR, ITGB6 and KIF20A, all genes governing cell proliferation and motility.

  2. Reduced expression of miR-98 may relate to LOX-1 expression and foam cell formation and lipid accumulation in aortas of ApoE(-/-) mice.

  3. hyperoside inhibits oxLDL-induced LOX-1 expression, ERK activation, and cell proliferation through the oxLDL-LOX-1-ERK pathway in VSMCs.

  4. data revealed that miR-let-7g exhibits anti-atherosclerotic activity, at least partially by targeting the LOX-1 signaling pathway.

  5. At low oxLDL levels LOX-1 activates the protective Oct-1/SIRT1 pathway, while at higher levels of the lipoprotein switches to the thrombogenic ERK1/2 pathway.

  6. Adiponectin, TNF-alpha, and LOX-1 exert complex regulatory effects on the coronary microvascular endothelial function in atherosclerotic ApoE knockout mice.

  7. LOX-1 in cardiomyocytes plays an important role in the pathology of doxorubicin-induced cardiomyopathy. LOX-1 deletion altered the LOX-1-related signaling pathway, which led to improvements in cardiac function, myocardial inflammation, fibrosis and degenerative changes after DOX treatment.

  8. Enzymatically modified low-density lipoprotein promotes foam cell formation in smooth muscle cells via macropinocytosis and enhances receptor-mediated uptake of oxidized low-density lipoprotein.

  9. Therefore we concluded that HNG could inhibit ox-LDL-induced macrophage-derived foam cell formation, which occurs because of a decrease in lipid uptake and an increase in cholesterol efflux from macrophage cells.

  10. The study indicated that the LOX-1/ox-LDL system in chondrocytes plays a role in the pathogenesis of age-related knee knee osteoarthritis, which is potentially a target for preventing knee osteoarthritis progression.

  11. We demonstrated that varenicline upregulates expression of LOX-1 and CD36 significantly through alpha7 nAChR, thereby promoting oxLDL uptake in macrophages.

  12. this study shows that LOX-1 can regulate inflammation through regulation of generation of reactive oxygen species in in Aspergillus fumigatus keratitis

  13. The in vitro and in vivo models revealed that lipid metabolism disorder and FK506 caused oxidative stress and a fibrogenic response. In addition, decreased levels of LOX1 markedly reduced the levels of TGFb1 in the in vitro model.

  14. LOX-1/ox-LDL system plays a pivotal role in the pathogenesis of instability-induced osteoarthritis through endochondral ossification.

  15. that ox-LDL receptor-1 and PCSK9 positively influence each other's expression, especially during an inflammatory reaction

  16. LOX1 is implicated in OxLDLinduced oxidative stress of macrophages in atherosclerosis, which in part, involves the regulation of NADPH oxidases.

  17. LOX-1 is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 and -2.

  18. mice with LOX-1 deletion given similar infusion of angiotensin II showed much less rise in blood pressure, and less expression of NADPH oxidase, activation of P38 MAPK and nuclear factor-kappaB, autophagy-related proteins and TLR4 than wild-type mice.

  19. LOX-1 plays an important role in ischemia-induced angiogenesis by 1) Nox2-ROS-NF-kappaB activation, 2) upregulated expression of adhesion molecules: VCAM-1 and LOX-1 and 3) promoting macrophage infiltration.

  20. Our findings indicate the novel involvement of LOX-1 in physiological bone homeostasis and inflammatory bone diseases.

Cow (Bovine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. Endothelial LOX-1 overexpression in an atherosclerosis-prone LDL receptor knockout mice impairs endothelial function, proving its importance in the development of atherosclerosis.

  2. bta-miR-370 has a negative regulatory effect on the OLR1 gene at both the gene and protein expression levels and has a role in lipid metabolism in bovine adipocytes

  3. Overexpression of LOX-1 leads to the attenuation of protective autophagy response in aortic endothelial cells.

  4. These results imply that the 3' UTR SNP of the OLR1 gene is a strong candidate marker for selection in cattle breeding programs.

  5. Our data indicate that blocking the LOX-1 receptor signal pathway might be a promising way to improve steroid hormone concentrations in metabolically highly active female mammals

  6. In the present study, we show that inhibition of LOX-1 leads to a rearrangement of ceramide from the basal membrane toward the Golgi apparatus

  7. The downregulation of eNOS by ox-low-density lipoprotein, as driven by LOX-1-mediated endoplasmic stress, is associated with the PI3K-Akt-eNOS signaling pathway.

  8. 3'-UTR SNP assoicated with milk composition traits and somatic cell score

  9. Disruption of lipid packing of cholesterol-rich membrane domains plays a key role in oxidized low-density lipoprotein (oxLDL)-induced changes in endothelial biomechanics.

  10. Oxidized low-density lipoprotein receptor (OLR1) single nucleotide polymorphism haplotype is associated with milk fat yield and fat percentage

  11. synergistic effects of cyclic tensile stretch load and ox-LDL on cell viability and proteoglycan synthesis in chondrocytes, which may be mediated through enhanced expression of LOX-1

  12. Upregulates VEGF expression in articular cartilage, at least in part, through activation of PPAR-gamma.

  13. Mediation of electronegative low-density lipoprotein signaling by LOX-1: a possible mechanism of endothelial apoptosis.

  14. ox-LDL binding to LOX-1 induces stress-induced senescence of chondrocytes and suppression of telomerase activity. Oxidized LDL may play an important role in the pathogenesis of osteoarthritis by inducing chondrocyte senescence.

OLR1 Antigen Profile

Antigen Summary

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with OLR1

  • oxidized low density lipoprotein receptor 1 (OLR1) antibody
  • oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1) antibody
  • oxidized low density lipoprotein receptor 1 (Olr1) antibody
  • CLEC8A antibody
  • LOX-1 antibody
  • LOX1 antibody
  • LOXIN antibody
  • Oldlr1 antibody
  • Oldr1 antibody
  • Olr1 antibody
  • PLOX-1 antibody
  • Scare1 antibody
  • SLOX1 antibody
  • SR-EI antibody

Protein level used designations for OLR1

oxidised low density lipoprotein (lectin-like) receptor 1 , oxidized low density lipoprotein (lectin-like) receptor 1 , lectin-like oxLDL receptor 1 , lectin-like oxidized LDL receptor 1 , lectin-type oxidized LDL receptor 1 , ox-LDL receptor 1 , oxidized low-density lipoprotein receptor 1 , C-type lectin domain family 8 member A , hLOX-1 , ox LDL receptor 1 , oxidized low-density lipoprotein receptor 1, soluble form , scavenger receptor class E, member 1 , Lectin-like oxidized low-density lipoprotein receptor-1 , lectin-like oxidized low-density lipoprotein receptor , BLOX1 , LOX-1 , bLOX-1 , lectin-like oxidized LDL receptor-1 , oxidized low density lipoprotein receptor 1

GENE ID SPECIES
473362 Pan troglodytes
486694 Canis lupus familiaris
100009322 Oryctolagus cuniculus
4973 Homo sapiens
108078 Mus musculus
140914 Rattus norvegicus
281368 Bos taurus
396724 Sus scrofa
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