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OSBPL6 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Additionally we are shipping Oxysterol Binding Protein-Like 6 Antibodies (31) and Oxysterol Binding Protein-Like 6 Proteins (6) and many more products for this protein.
family-based GWAS of imputed SNPs revealed novel genomic variants in (or near) PTPRG (show PTPRG ELISA Kits), OSBPL6, and PDCL3 (show PDCL3 ELISA Kits) that influence risk for Alzheimer's Disease. rs7609954 in the gene PTPRG (show PTPRG ELISA Kits), rs1347297 in the gene OSBPL6, and rs1513625 near PDCL3 (show PDCL3 ELISA Kits). In addition, rs72953347 in OSBPL6 and two SNPs in the gene CDKAL1 (show CDKAL1 ELISA Kits) showed marginally significant association with LOAD (rs10456232, P-value=4.76 x 10-7; rs62400067, P-value=3.54 x 10-7).
Oxysterol-binding protein-like 6 is a novel regulator of cholesterol trafficking that is part of the miR (show MLXIP ELISA Kits)-33 and miR (show MLXIP ELISA Kits)-27b target gene networks contributing to the maintenance of cholesterol homeostasis.
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified.
, OSBP-related protein 6
, oxysterol-binding protein-related protein 6