PGD Synthetase Proteins

Protein Summary

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Gene names and symbols associated with PGD Synthetase Proteins (PGDS)

• prostaglandin D2 synthase (brain) (Ptgds) antibody
• prostaglandin D2 synthase (Ptgds) antibody
• prostaglandin D2 synthase (PTGDS) antibody

• 21kDa antibody
• L-PGDS antibody
• LPGDS antibody
• PDS antibody
• PGD2 antibody
• Show all synonym aliases
• PGDS antibody
• PGDS2 antibody
• PH2DISO antibody
• Ptgs3 antibody

Protein level used designations for PGD Synthetase Proteins (PGDS)

PGD2 synthase , glutathione-independent PGD synthase , glutathione-independent PGD synthetase , lipocalin-type prostaglandin-D synthase , prostaglandin D2 synthase (21 kDa, brain) , prostaglandin-D2 synthase , prostaglandin-H2 D-isomerase , PGDS , PGDS2 , Prostaglandin D synthase , beta-trace protein , cerebrin-28 , lipocalin-type prostaglandin D synthase , prostaglandin D synthase