anti-POU Class 2 Associating Factor 1 (POU2AF1) Antibodies

Transcriptional coactivator that specifically associates with either OCT1 or OCT2. Additionally we are shipping POU2AF1 Proteins (8) and POU2AF1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
POU2AF1 5450 Q16633
POU2AF1 690528  
POU2AF1 18985 Q64693
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Top anti-POU2AF1 Antibodies at

Showing 10 out of 152 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometry analysis of Ramos cells (bottom histogram) using POU2AF1 Antibody compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POU2AF1 Antibody (N-term) AP53397PU-N for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
Mouse Goat Un-conjugated ELISA, WB ABIN184851 staining (2µg/ml) of mouse spleen lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
Dog Goat Un-conjugated WB   0.1 mg Log in to see 12 to 15 Days
Human Mouse Un-conjugated WB POU2AF1 Antibody (ABIN1882276) western blot analysis in Daudi cell line lysates (35 µg/lane). This demonstrates the POU2AF1 antibody detected the POU2AF1 protein (arrow). 400 μL Log in to see 10 to 11 Days
Bat Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
Mouse Rabbit Un-conjugated IHC (p), WB Anti-BOB1 antibody, Western blotting Lane: Rat Spleen Tissue Lysate Anti-BOB1 antibody, IHC(P) IHC(P): Rat Tonsil Tissue 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
Human Goat Un-conjugated IHC, ELISA, WB lysate (10ug protein in RIPA buffer) overexpressing Human POU2AF1 with DYKDDDDK tag probed with EB10018(1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/3000) in lane C. Mock-transfected HEK293 probed with EB10018(1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
Cow Goat Un-conjugated EIA, IHC (p), WB Paraffin Embedded Human Spleen using POU2AF1 / BOB1 Antibody  shows nuclear staining in the germinal center with stronger nucleoli staining in some of the B cells. HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human POU2AF1 with <em>DYKDDDDK tag</em> probed with POU2AF1 Antibody  (1 µg/ml) in Lane A and probed with anti-<em>DYKDDDDK Tag</em> (1/3000) in Lane C. Mock-transfected HEK293 probed with POU2AF1 Antibody AP32080PU-N (1 mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB 1 mL Log in to see 2 to 3 Days

POU2AF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-POU2AF1 Antibodies

  1. Human Monoclonal POU2AF1 Primary Antibody for WB - ABIN1882276 : Galiègue-Zouitina, Quief, Hildebrand, Denis, Lecocq, Collyn-dHooghe, Bastard, Yuille, Dyer, Kerckaert: Fusion of the LAZ3/BCL6 and BOB1/OBF1 genes by t(3; 11) (q27; q23) chromosomal translocation. in Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1996 (PubMed)
    Show all 4 Pubmed References

  2. Mouse (Murine) Polyclonal POU2AF1 Primary Antibody for ELISA, WB - ABIN249690 : Strubin, Newell, Matthias: OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. in Cell 1995 (PubMed)

More Antibodies against POU2AF1 Interaction Partners

Human POU Class 2 Associating Factor 1 (POU2AF1) interaction partners

  1. These findings demonstrate for the first time that functional polymorphism in the 3'-UTR (show UTS2R Antibodies) of POU2AF1 is associated with susceptibility, and that single-nucleotide polymorphisms interaction with hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-633 affects gene expression and increases the risk of lymphoma.

  2. Oct2 and Bob1 are very reliable in determining B cell lineage in the absence of expression of other pan (show SUPT6H Antibodies)-B cell markers

  3. these findings suggest a novel function of POU2AF1 as a potential regulator of host defense genes in the human airway epithelium.

  4. It has been identified as a new disease susceptibility gene among Japanese. Though different from Europeans, it is indicated that a B lymphocyte differentiation route shares a common disease developing process. [Review]

  5. Two significant susceptibility loci, TNFSF15 (show TNFSF15 Antibodies) (rs4979462) and POU2AF1 (rs4938534) (combined odds ratio [OR] = 1.56, p = 2.84 x 10(-14) for rs4979462.

  6. Data show that Igh 3' enhancer-bound OCA-B and promoter-bound TFII-I mediate promoter-enhancer interactions, in both cis and trans, that are important for Igh transcription.

  7. Twenty-two cases of nodular lymphocyte predominant Hodgkin lymphoma were studied for the immunohistochemical expression of Pax-5 (show PAX5 Antibodies), Oct-2, BOB.1, Bcl-6 (show BCL6 Antibodies) protein and MUM1/IRF-4 (show IRF4 Antibodies).

  8. On multivariate analysis, co-expression of OCT-2/BOB.1 remained predictive for achievement of complete remission and increased risk of relapse.

  9. The expression of the octamer cofactor gene OBF-1 (Bob1/OCA-B) is sufficient to override the silencing effects of the B29 (show CD79B Antibodies) silencer, indicating that OBF-1 plays a critical role in B cell-specific B29 (show CD79B Antibodies) promoter expression.

  10. enhances transcriptional potential of Oct1 (show POU2F1 Antibodies)

Mouse (Murine) POU Class 2 Associating Factor 1 (POU2AF1) interaction partners

  1. Bob1 promotes the development of follicular T helper cells via Bcl6 (show BCL6 Antibodies).Bob1 is directly involved in follicular T helper cell differentiation and required for mounting normal T cell-dependent B-cell responses.

  2. Findings indicate octamer transcription factor-1 (show HNF1A Antibodies) (Oct1 (show POU2F1 Antibodies)) and Oct binding factor 1 protein (OCA-B) as central mediators of CD4 (show CD4 Antibodies)(+) T cell memory.

  3. overexpression of DDX60 (show DDX60 Antibodies) did not potentiate IFN induction

  4. Loss of Obf1 is associated with IgM-mediated glomerulonephritis.

  5. The transcription factor Bob1 counteracts B cell activation (show BLNK Antibodies) and regulates miR (show MLXIP Antibodies)-146a in B cells.

  6. Expressing a stable Bob1 mutant in B cells suppresses cell proliferation and induces changes in surface marker expression commonly seen during B-cell differentiation.

  7. Data show that IL-6 (show IL6 Antibodies) and IL-21 (show IL21 Antibodies) act with different kinetics during the germinal centers (GCs (show UGCG Antibodies)) response and that B cells, in an Oct2 (show SLC22A2 Antibodies)/OBF-1-dependent manner, can supply the IL-6 (show IL6 Antibodies) for early induction of T follicular helper cells (T(FH) development.

  8. OcaB is essential for V(D)J recombination of a subset of Igkappa genes. We show that OcaB modulates recombination by directly enhancing Igkappa gene transcription in vivo.

  9. Data show that the expression of BOB.1/OBF (show IZUMO1 Antibodies).1 in peripheral B cells is required for the development of marginal zone B lymphocytes.

  10. Transcriptional coactivator OBF-1 is essential for germinal center formation in Aiolos (show IKZF3 Antibodies)-deficient mice; lack of OBF-1 reverses several Aiolos (show IKZF3 Antibodies) mutant mouse phenotypes.

POU2AF1 Antigen Profile

Protein Summary

Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.

Gene names and symbols associated with POU2AF1

  • POU class 2 associating factor 1 (POU2AF1) antibody
  • POU class 2 associating factor 1 (Pou2af1) antibody
  • POU domain, class 2, associating factor 1 (Pou2af1) antibody
  • Bob-1 antibody
  • BOB.1 antibody
  • Bob1 antibody
  • OBF-1 antibody
  • OBF.1 antibody
  • OBF1 antibody
  • OCA-B antibody
  • OCAB antibody

Protein level used designations for POU2AF1

B-cell-specific coactivator OBF-1 , BOB-1 , OCA-B , OCT-binding factor 1 , POU domain class 2-associating factor 1 , POU domain, class 2, associating factor 1 , OCT binding factor 1

5450 Homo sapiens
528475 Bos taurus
690528 Rattus norvegicus
18985 Mus musculus
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