anti-POU Domain, Class 2, Transcription Factor 1 (POU2F1) Antibodies

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Additionally we are shipping POU2F1 Kits (26) and POU2F1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
POU2F1 5451 P14859
POU2F1 171068 P31503
POU2F1 18986 P25425
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Top anti-POU2F1 Antibodies at antibodies-online.com

Showing 10 out of 151 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-POU2F1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
€255.75
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-POU2F1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Transfected 293T POU2F1 is supported by BioGPS gene expression data to be expressed in HEK293T WB Suggested Anti-POU2F1  Antibody Titration: 0.2-1 µg/mL  Positive Control: Transfected 293T POU2F1 is supported by BioGPS gene expression data to be expressed in HEK293T 100 μL Log in to see 2 to 3 Days
€255.75
Details
Mouse Rabbit Un-conjugated WB WB Suggested Anti-POU2F1 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:62500  Positive Control:  SP2/0 cell lysate 100 μL Log in to see 2 to 3 Days
€202.65
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- Oct-1 Picoband antibody, Western blotting All lanes: Anti Oct-1  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Human Placenta Tissue Lysate at 50ug Lane 3: JURKAT Whole Cell Lysate at 40ug Lane 4: HELA Whole Cell Lysate at 40ug Lane 5: A549 Whole Cell Lysate at 40ug Lane 6: SMMC Whole Cell Lysate at 40ug Predicted bind size: 90KD Observed bind size: 90KD 100 μg Log in to see 4 to 6 Days
€247.79
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
€380.39
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Small intestine lysate; Primary Ab: 3µg/ml Rabbit Anti-Mouse OCT1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 15 to 18 Days
€302.65
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2 cells, using POU2F1/OCT1 (Ab-385) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
€267.70
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue using POU2F1 antibody (Center)  cat.no. AP53398PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining.Clinical relevance has not been evaluated. Western blot analysis in HL-60 cell line lysates (35ug/lane) detecting POU2F1 protein (arrow) by the use of POU2F1 0.4 mL Log in to see 6 to 8 Days
€345.58
Details
Human Rabbit Un-conjugated IHC (p), WB POU2F1 Antibody (Center)  western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the POU2F1 antibody detected the POU2F1 protein (arrow). POU2F1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POU2F1 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
€340.71
Details
Bat Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
€540.27
Details

Top referenced anti-POU2F1 Antibodies

  1. Mouse (Murine) Polyclonal POU2F1 Primary Antibody for WB - ABIN2780176 : Tantin, Schild-Poulter, Wang, Haché, Sharp: The octamer binding transcription factor Oct-1 is a stress sensor. in Cancer research 2005 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal POU2F1 Primary Antibody for IHC (fro), IP - ABIN549411 : Gao, Zhao, Kong, Toselli, Chou, Stone, Li: Cloning and characterization of the rat lysyl oxidase gene promoter: identification of core promoter elements and functional nuclear factor I-binding sites. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 Pubmed References

  3. Polyclonal POU2F1 Primary Antibody for DB, IHC (fro) - ABIN541090 : Mesplède, Island, Christeff, Petek, Doly, Navarro: The POU transcription factor Oct-1 represses virus-induced interferon A gene expression. in Molecular and cellular biology 2005 (PubMed)

  4. Human Monoclonal POU2F1 Primary Antibody for ELISA, WB - ABIN519045 : Sánchez, Palomino-Morales, Ortego-Centeno, Jiménez-Alonso, González-Gay, López-Nevot, Sánchez-Román, de Ramón, González-Escribano, Pons-Estel, DAlfonso, Sebastiani, Alarcón-Riquelme, Martín: Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus. in Human molecular genetics 2009 (PubMed)

More Antibodies against POU2F1 Interaction Partners

Human POU Domain, Class 2, Transcription Factor 1 (POU2F1) interaction partners

  1. Changes in the expression level of Oct-1A, Oct-1L, Oct-1X, and Oct-1Z isoforms and CD14 surface antigen during differentiation of HL-60 monocytic cells induced in vitro by dimethyl sulfoxide were studied, and the expression level of the four Oct-1 isoforms in vivo in human monocytes was determined.

  2. E6/E7-p53-POU2F1-CTHRC1 axis promotes cervical cancer cell invasion and metastasis

  3. our results indicate that POU2F1 over-expression is positively associated with aggressive phenotypes and poor survival in patients with HCC, and POU2F1 regulated by AKT pathway promotes HCC aggressive phenotypes by regulating the transcription of EMT genes.

  4. A significant influence of OCT1 mRNA expression on the clinical outcome of the disease was observed.

  5. Children with certain OCT1 genotypes have higher risk for respiratory depression and nausea and vomiting, postoperatively, following morphine administration.

  6. High POU2F1 expression is associated with liver cancer.

  7. THE results of this investigation demonstrate that genetic polymorphisms in the hepatic uptake transporter OCT1 affect the pharmacokinetics and efficacy of tramadol.

  8. Hepatic distribution of metformin was significantly reduced after oral administration in individuals with genetic polymorphisms in OCT1.

  9. We found that a combination of two polymorphisms in hOCT1 that seem to play the role of predictor for imatinib in both efficacy and toxicity

  10. hOCT1 mRNA expression may serve as a clinical biomarker of response to imatinib and could be useful to predict Imatinib mesylate therapy outcome of chronic myeloid leukemia patients

  11. ABCB1 and OCT1 mRNA expressions may present biological relevance to identify responder and non-responder patients to imatinib treatment

  12. Our study demonstrates that the existence of Oct-1 isoforms which vary in length and sequence at the N-terminus of the protein, also contributes in surprising diversity of Oct-1 functions in transcription regulation.

  13. HLA-C Level Is Regulated by a Polymorphic Oct1 Binding Site in the HLA-C Promoter Region

  14. OCT1 transported sumatriptan with high capacity and sumatriptan uptake into human hepatocytes was strongly inhibited by the OCT1 inhibitor MPP(+)

  15. Neither AUC0-150min, ktr, CL, nor VD were associated with genetic variants in OCT1, ABCB1, and UGT2B7 (all P>0.05).

  16. Oct-1 modifies S100A4 exchange between intra- and extracellular compartments in Namalwa cells and increases their sensitivity to glucocorticoids.

  17. Low expression of POU2F1 is associated with osteosarcoma.

  18. Data indicate that octamer transcription factor 1 (OCT1; pou2f1) expression levels are significantly upregulated in colorectal cancer.

  19. Comparative analysis of various tumor lines showed no clear correlation between the expression level of Mts1/S100A4 and the content of Oct-1. However, at stable transfection of tumor cells with Oct-1A, Oct-1L, and Oct-1X isoforms we detected an elevated level of Oct-1, which stimulated Mts1/S100A4 secretion.

  20. The response in Burkitt's lymphoma cells (Namalwa line) to camptothecin and dexamethasone of the Oct-1 target genes involved in the development of apoptosis depended, firstly, on the type of drug, secondly, on the concentration of Oct-1 in cells and, thirdly, on the Oct-1 isoform with which these cells were transfected

Mouse (Murine) POU Domain, Class 2, Transcription Factor 1 (POU2F1) interaction partners

  1. In embryonic stem cells, Oct1 co-occupies a specific set of targets with Oct4, but does not occupy differentially expressed developmental targets. Instead, Oct1 occupies these targets as cells differentiate and Oct4 declines.

  2. At low oxLDL levels LOX-1 activates the protective Oct-1/SIRT1 pathway, while at higher levels of the lipoprotein switches to the thrombogenic ERK1/2 pathway.

  3. Study conclude that pentamidine interacts with multiple transporters, is taken into brain endothelial cells by OCT1 transporter and is extruded into the blood by ATP-dependent mechanisms. These interactions along with the predominant presence of OCT1 in the luminal membrane of the BBB contribute to the limited entry of pentamidine into the brain.

  4. These results suggest that Oct-1 and GATA-3/Oct-2 direct Th2 cytokine gene expression in a cooperative manner.

  5. Findings indicate octamer transcription factor-1 (Oct1) and Oct binding factor 1 protein (OCA-B) as central mediators of CD4(+) T cell memory.

  6. levels of microRNA-451 (miR-451) are negatively regulated through the phosphorylation and inactivation of its direct transcriptional activator OCT1 by 5' AMP-activated protein kinase

  7. Oct1 mRNA expression was decreased in mice with both ob/ob and methionine/choline deficiency models of nonalcoholic steatohepatitis.

  8. OCT1 is a driver of synbindin-mediated ERK signalling and a promising marker for the prognosis and molecular subtyping of gastric cancer.

  9. studies implicate OCT1 as well as metformin in thiamine disposition, suggesting an intriguing and parallel mechanism for metformin and its major hepatic transporter in metabolic function.

  10. Th17 lineage differentiation is restrained by the Th2 locus via interchromosomal associations organized by Oct-1 and CTCF.

  11. inhibition of the DNA binding activity of transcriptional repressor OCT-1 is a mechanism by which ethanol up-regulates Slc711 expression.

  12. mammary cells express beta-casein in response to prolactin in a pathway that involves gap junction intracellular communication and OCT-1 and is independent of STAT5 nuclear translocation

  13. Oct1 plays an important role not only in the pharmacokinetics of cis-diammine(pyridine)chloroplatinum(II)(CDPCP), but also in its toxicities.

  14. role for Oct1 in mitosis

  15. Oct-1 serves as a sensor for both metabolic as well as stress/survival signals.

  16. Oct1 appears to be a critical mediator of the growth arrest induced by mTOR inhibition via the control of p27(Kip1) expression.

  17. Oct1 is a switchable stabilizer of repressed and inducible states of transcription

  18. Oct1 is required in th embryo proper from late gastrulation stages onwards.

  19. OCT1 and OCT2 are important for N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) transfer across the blood-brain barrier and amantadine reduces the blood-brain barrier transfer of MPTP and MPTP-induced dopaminergic toxicity in rodents.

  20. analysis of a tethered-hopping model for protein-DNA binding and unbinding based on Sox2-Oct1-Hoxb1 ternary complex simulations

Xenopus laevis POU Domain, Class 2, Transcription Factor 1 (POU2F1) interaction partners

  1. identified Oct-1 (POU2f1), a POU transcription factor, as a downstream target of Notch signaling by microarray based screen

Cow (Bovine) POU Domain, Class 2, Transcription Factor 1 (POU2F1) interaction partners

  1. The results from this study clearly demonstrate the involvement of octamer transcription factor-1 in the regulation of tracheal antimicrobial peptide and lingual antimicrobial peptide expression.

POU2F1 Antigen Profile

Protein Summary

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993

Gene names and symbols associated with POU2F1

  • POU class 2 homeobox 1 (POU2F1) antibody
  • POU class 2 homeobox 1 (Pou2f1) antibody
  • POU domain, class 2, transcription factor 1 (Pou2f1) antibody
  • POU class 2 homeobox 1 S homeolog (pou2f1.S) antibody
  • POU class 2 homeobox 1b (pou2f1b) antibody
  • 2810482H01Rik antibody
  • chOCT-1 antibody
  • fc07d06 antibody
  • NF-A1 antibody
  • oct-1 antibody
  • oct-1B antibody
  • oct1 antibody
  • Otf-1 antibody
  • Otf1 antibody
  • POU2F1 antibody
  • pou2f1r antibody
  • wu:fc07d06 antibody
  • zgc:158360 antibody

Protein level used designations for POU2F1

NF-A1 , OTF-1 , Octamer-binding transcription factor-1 , POU domain, class 2, transcription factor 1 , oct-1 , octamer-binding protein 1 , octamer-binding transcription factor 1 , POU class 2 homeobox 1 , ubiquitous transcription factor , octamer-binding protein (Oct-1) , octamer binding protein 1 , XOct1 , maternal transcription factor , xloct1-32

GENE ID SPECIES
5451 Homo sapiens
171068 Rattus norvegicus
457486 Pan troglodytes
490360 Canis lupus familiaris
18986 Mus musculus
396463 Gallus gallus
397501 Sus scrofa
399316 Xenopus laevis
100735919 Cavia porcellus
512840 Bos taurus
323702 Danio rerio
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