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The protein encoded by PRPF4 is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. Additionally we are shipping PRP4 Pre-MRNA Processing Factor 4 Homolog (Yeast) Antibodies (19) and many more products for this protein.
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The p.R192H variant of PRPF4 represents a functional null allele which compromises the function of the tri (show VANGL2 Proteins)-snRNP (show LSM2 Proteins), reinforcing the notion that this spliceosomal particle is of crucial importance in the physiology of the retina.
PRPF4 missense mutations is associated with autosomal dominant retinitis pigmentosa.
the requirement of enzymatic activity of PRP4 (show PRPF4B Proteins) in regulating cancer cell growth and identified an array of potential novel substrates through orthogonal proteomics approaches
interaction between Hprp3p (show PRPF3 Proteins) and Hprp4p
PRP4 (show PRPF4B Proteins) is a spindle assembly checkpoint protein required for MPS1 (show IDUA Proteins), MAD1 (show MXD1 Proteins), and MAD2 (show MAD2L1 Proteins) localization to the kinetochores.
PRP-4 (show PRPF4B Proteins) belongs to the serine/threonine protein kinase (show PRKACG Proteins) family, plays a role in pre-mRNA splicing and cell mitosis, and interacts with CLK1 (show CDK11B Proteins)
The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Two transcript variants encoding different isoforms have been found for this gene.
U4/U6 small nuclear ribonucleoprotein Prp4
, PRP4 pre-mRNA processing factor 4 homolog (yeast)
, WD40 repeat-containing protein
, pre-mRNA processing factor 4
, U4/U6 small nuclear ribonucleoprotein Prp4-like
, PRP4 homolog
, PRP4/STK/WD splicing factor
, U4/U6 snRNP 60 kDa protein
, WD splicing factor Prp4