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PLXNC1 encodes a member of the plexin family. Additionally we are shipping Plexin C1 Antibodies (34) and Plexin C1 Kits (3) and many more products for this protein.
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PLXNC1 and RDH13 are associated with bilateral convergent strabismus with exophthalmus in German Brown cattle.
Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin c1 has been described.
Results indicate that long non-coding RNA (lncRNA) CASC2 can promote PLXNC1 expression by sponging miR-181a, thereby inhibiting the proliferation and invasion of melanoma cells.
Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis
loss of Plexin C1 in melanoma may promote early steps in melanoma progression through suppression of migration and proliferation
Study reports the structures of Sema7A and A39R complexed with the Semaphorin-binding module of PlexinC1; both structures show two PlexinC1 molecules symmetrically bridged by Semaphorin dimers.
GTP-bound form of Rab7 promotes melanogenesis through the regulation of gp100 maturation in melanoma cells.
Plexin C1, a receptor for semaphorin 7a, inactivates cofilin and is a potential tumor suppressor for melanoma progression.
significant loss of Plexin C1 in metastatic melanoma compared with primary melanoma, suggesting the possibility that the Plexin C1 receptor is a tumor suppressor protein for melanoma
Sema7A-PlxnC1 interaction is essential to form the post-synaptic assembly.
Plxnc1 interaction with Sema7a mediates repulsion of ventral tegmental area neurons.Lmx1a and Lmx1b regulate Plxnc1 expression.
These results implicate an important role of PLXNC1 during an acute inflammatory response and indicate PLXNC1 as a potential target for the control of conditions associated with acute inflammation.
PlexinC1 gene expression regulation is expressed within the hypohalamic nucleus and supraoptic hypothalamus.
Plexin-C1 displayed R-Ras GAP activity and inhibited cell migration
This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene.
, plexin (semaphorin receptor)
, receptor for viral semaphorin protein
, receptor for virally-encoded semaphorin
, virus-encoded semaphorin protein receptor
, viral-encoded semaphorin protein receptor