Polymerase (DNA-Directed), delta Interacting Protein 2 (POLDIP2) ELISA Kits

POLDIP2 encodes a protein that interacts with the DNA polymerase delta p50 subunit. Additionally we are shipping POLDIP2 Antibodies (60) and POLDIP2 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human POLDIP2 POLDIP2 26073 Q9Y2S7
Anti-Mouse POLDIP2 POLDIP2 67811 Q91VA6
Anti-Rat POLDIP2 POLDIP2 287544  
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More ELISA Kits for POLDIP2 Interaction Partners

Human Polymerase (DNA-Directed), delta Interacting Protein 2 (POLDIP2) interaction partners

  1. findings establish that PolDIP2 can regulate the translesion synthesis polymerase and primer extension activities of PrimPol

  2. POLDIP2 plays a crucial role in Tau aggregation via the impairment of autophagy activity, providing insight into Tau aggregation in Tau pathology.

  3. PDIP38 can respond to genotoxic or transcriptional stresses by undergoing translocation to the spliceosomes, where it is a required participant in the regulation of MDM2 (show MDM2 ELISA Kits) alternative splicing.

  4. DNA polymerase delta-interacting protein 2 is a processivity factor for DNA polymerase lambda (show POLL ELISA Kits) during 8-oxo-7,8-dihydroguanine bypass.

  5. We demonstrate that PDIP38 (Poldelta interacting protein of 38kDa (show RFC3 ELISA Kits)) directly interacts with the TLS (show FUS ELISA Kits) polymerase Poleta. PDIP38 is able to interact directly not only with Poleta but also with the specialized polymerases Rev1 (show REV1 ELISA Kits) and Polzeta (via Rev7 (show MAD2L2 ELISA Kits)).

  6. suggest that the TNFAIP1 (show TNFAIP1 ELISA Kits)/POLDIP2 complex sense-antisense architecture represents a clinically significant transcriptional structural-functional gene module associated with amplification of the genomic region on 17q11.2 in breast cancer.

  7. PDIP38 might play a role in the pol delta (show POLD1 ELISA Kits)-mediated viral DNA replication

  8. PDIP38 is located in the mitochondrial matrix. TFAM (show TFAM ELISA Kits) and mitochondrial single-stranded DNA binding protein (show RPA1 ELISA Kits) (mtSSB) are co-immunoprecipitated with PDIP38

  9. PDIP38 can shuttle between the cytoplasmic and the nuclear compartments and that its subcellular localization is regulated by CEACAM1 (show CEACAM1 ELISA Kits)

  10. Poldip2 associates with p22phox (show CYBA ELISA Kits) to activate Nox4 (show NOX4 ELISA Kits), leading to regulation of focal adhesion turnover and vascular smooth muscle cell migration, thus linking reactive oxygen species production and cytoskeletal remodeling.

Mouse (Murine) Polymerase (DNA-Directed), delta Interacting Protein 2 (POLDIP2) interaction partners

  1. the rate of collagen I degradation was increased in Poldip2(+/-) vs. Poldip2(+/+) MASMs. Conversely, activation of the PI3K/Akt (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) signaling pathway, involved in regulation of protein synthesis, was significantly elevated in Poldip2(+/-) MASMs as was beta1-integrin expression.

  2. Poldip2 is an essential protein in development, and underline its importance in cell viability and proliferation

  3. Suggest Poldip2 promotes ischemia-induced collateral vessel formation via multiple mechanisms that likely involve reactive oxygen species-dependent activation of matrix metalloproteinase activity, as well as enhanced vascular cell growth and survival.

  4. Poldip2 expression is necessary for maintainance vascular integrity and function.

  5. miR (show MLXIP ELISA Kits)-291a-5p directly inhibited the expression of PDIP38.

  6. overexpression of Mitogenin I or mitochondrial single-stranded DNA-binding protein (show RPA1 ELISA Kits) increased elongated or fragmented mitochondria in mouse C2C12 myoblast cells, respectively.

POLDIP2 Antigen Profile

Antigen Summary

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. The encoded protein also interacts with proliferating cell nuclear antigen. Some transcripts of this gene overlap in a tail-to-tail orientation with the gene for tumor necrosis factor, alpha-induced protein 1 (TNFAIP1).

Gene names and symbols associated with POLDIP2

  • DNA polymerase delta interacting protein 2 (POLDIP2) antibody
  • polymerase (DNA-directed), delta interacting protein 2 (Poldip2) antibody
  • DNA polymerase delta interacting protein 2 (Poldip2) antibody
  • polymerase (DNA-directed), delta interacting protein 2 L homeolog (poldip2.L) antibody
  • polymerase (DNA-directed), delta interacting protein 2 (poldip2) antibody
  • 1300003F06Rik antibody
  • fc11h12 antibody
  • Pdip38 antibody
  • POLD4 antibody
  • wu:fc11h12 antibody
  • wu:fi22f04 antibody

Protein level used designations for POLDIP2

38 kDa DNA polymerase delta interaction protein , p38 , polymerase delta interacting protein 38 , polymerase delta-interacting protein 2 , mitogenin 1 , mitogenin I , DNA-directed polymerase delta interacting protein 2 , DNA polymerase delta interacting protein 2 , polymerase (DNA-directed), delta interacting protein 2 , polymerase (DNA) delta interacting protein 2

26073 Homo sapiens
67811 Mus musculus
287544 Rattus norvegicus
491162 Canis lupus familiaris
539673 Bos taurus
432266 Xenopus laevis
549852 Xenopus (Silurana) tropicalis
707994 Macaca mulatta
100019497 Monodelphis domestica
100481398 Ailuropoda melanoleuca
100598404 Nomascus leucogenys
100727945 Cavia porcellus
100000398 Danio rerio
100072037 Equus caballus
100348174 Oryctolagus cuniculus
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