Potassium Channel, Subfamily K, Member 9 Proteins (KCNK9)

KCNK9 encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains, and is highly expressed in the cerebellum. Additionally we are shipping KCNK9 Antibodies (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KCNK9 223604 Q3LS21
KCNK9 51305 Q9NPC2
Rat KCNK9 KCNK9 84429 Q9ES08
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Top KCNK9 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,626.01
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Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,355.45
Details

KCNK9 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
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Human ,
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More Proteins for Potassium Channel, Subfamily K, Member 9 (KCNK9) Interaction Partners

Mouse (Murine) Potassium Channel, Subfamily K, Member 9 (KCNK9) interaction partners

  1. Acute hypercapnia (5% CO2) stimulated ventilation in TASK-1 (show KCNK3 Proteins)/3(-/-) and wild-type mice to a similar extent; however, at higher CO2 concentrations the stimulation of ventilation was more pronounced in TASK-1 (show KCNK3 Proteins)/3(-/-) mice. At hyperoxia (100% O2), TASK-1 (show KCNK3 Proteins)(-/-), TASK-3(-/-) and wild-type mice showed the physiological small decrease of ventilation. TASK-1 (show KCNK3 Proteins)/3(-/-) mice exhibited an abnormal increase of ventilation under hyperoxia.

  2. results demonstrate that neurotensin (NT (show NTS Proteins)) transiently increased the neuronal excitability of dentate gyrus granule cells (GCs (show UGCG Proteins)) by inhibiting TASK-3 channels; NT-mediated increases in neuronal excitability facilitate long-term potentiation at the perforant path-GC synapses

  3. KCNK9 channels are not involved in hearing.

  4. THe results of this study suggested that dysfunction of KCNK9 causes a migration defect in the cortex via an activity-dependent mechanism.

  5. Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 (show KCNK3 Proteins) and TASK-3 channels in mouse carotid body type-1 cells.

  6. Data indicate that in 1-day-old Task3-/- mice, renal renin (show REN Proteins) concentration was lower than in wild-type mice.

  7. DPP6 (show DPP6 Proteins) co-expression with TASK-3 results in the formation of a protein complex that enhances resting membrane potassium conductance.

  8. An extracellular ion pathway plays a central role in the cooperative gating of a K(2P) K+ channel (show KCNC4 Proteins) by extracellular pH

  9. Task3 plays an important role in the adaptation of aldosterone secretion to dietary salt intake.

  10. This study demonistrated that kcnk9 gene expression in mouse dorsal raphe nucleus

Human Potassium Channel, Subfamily K, Member 9 (KCNK9) interaction partners

  1. observations implicate TASK-3 as a critical factor in cell cycle progression and corroborate its potential as a therapeutic target in breast cancer treatment.

  2. point mutations in DLK1 (show DLK1 Proteins) and KCNK9 at least do not seem to be a common cause of central precocious puberty in girls.

  3. In conclusion, we have identified the first selective activator of the two-pore domain potassium channel TASK3.

  4. KCNK9 imprinting syndrome is a rare cause of intellectual disability, congenital hypotonia, palatal abnormalities, and occasional seizures.

  5. Our results provide evidence for new loci influencing abdominal visceral (BBS9 (show BBS9 Proteins), ADCY8 (show ADCY8 Proteins), KCNK9) and subcutaneous (MLLT10 (show MLLT10 Proteins)/DNAJC1 (show DNAJC1 Proteins)/EBLN1 (show EBLN2 Proteins)) fat, and confirmed a locus (THNSL2 (show THNSL2 Proteins)) previously reported to be associated with abdominal fat in women.

  6. TASK-1 (show KCNK3 Proteins) and TASK-3 may form heterodimers in human atrial cardiomyocytes.

  7. During conductance simulation experiments, both TASK-3 and TREK-1 (show KCNK2 Proteins) channels were able to repolarise the membrane once AP threshold was reached

  8. The findings of this study suggest that variations in KCNK9 genes are associated with both mild and severe persistent breast pain after breast cancer surgery.

  9. Diacylglycerol mediates regulation of TASK1 and TASK3 potassium channels by GNAQ.

  10. Interference with TASK-3 channel expression, therefore, induces caspase (show CASP3 Proteins)-dependent and -independent apoptosis of melanoma cells, most likely via causing mitochondrial depolarization.

Guinea Pig Potassium Channel, Subfamily K, Member 9 (KCNK9) interaction partners

  1. An extracellular ion pathway plays a central role in the cooperative gating of a K(2P) K+ channel (show KCNC4 Proteins) by extracellular pH

KCNK9 Protein Profile

Protein Summary

This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains, and is highly expressed in the cerebellum. Amplification and overexpression of this gene has been observed in several types of human carcinomas, notably in breast cancer. This gene is imprinted in fetal brain, with preferential expression from the maternal allele.

Gene names and symbols associated with KCNK9

  • potassium channel, subfamily K, member 9 (Kcnk9)
  • potassium two pore domain channel subfamily K member 9 (KCNK9)
  • potassium two pore domain channel subfamily K member 9 (Kcnk9)
  • potassium channel, subfamily K, member 9 (kcnk9)
  • potassium channel, two pore domain subfamily K, member 9 (kcnk9)
  • potassium channel, two pore domain subfamily K, member 9 L homeolog (kcnk9.L)
  • k2p9.1 protein
  • Kcnk9 protein
  • kt3.2 protein
  • LOC799704 protein
  • task-3 protein
  • task3 protein

Protein level used designations for KCNK9

TWIK-related acid-sensitive K(+) channel 3 , acid-sensitive potassium channel protein TASK-3 , potassium channel subfamily K member 9 , TWIK-related acid-sensitive K+ channel 3 , potassium channel TASK3 , two pore K(+) channel KT3.2 , two pore potassium channel KT3.2 , potassium channel subfamily K member 9 (Task-3) , potassium channel, subfamily K, member 9 (Task-3) , potassium channel, subfamily K, member 9

GENE ID SPECIES
223604 Mus musculus
51305 Homo sapiens
84429 Rattus norvegicus
464416 Pan troglodytes
539586 Bos taurus
799704 Danio rerio
100135568 Cavia porcellus
100379982 Xenopus (Silurana) tropicalis
494803 Xenopus laevis
482057 Canis lupus familiaris
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