Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 ELISA Kits

Protein Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Gene names and symbols associated with KCNJ3

• potassium voltage-gated channel subfamily J member 3 (KCNJ3) antibody
• potassium inwardly-rectifying channel, subfamily J, member 3 (Kcnj3) antibody
• potassium voltage-gated channel subfamily J member 3 (Kcnj3) antibody

• girk1 antibody
• Kcnf3 antibody
• KGA antibody
• Kir3.1 antibody

Protein level used designations for KCNJ3

G protein-activated inward rectifier potassium channel 1 , GIRK-1 , inward rectifier K(+) channel Kir3.1 , inward rectifier K+ channel KIR3.1 , potassium channel, inwardly rectifying subfamily J member 3 , potassium inwardly-rectifying channel subfamily J member 3 splice variant 1e , potassium inwardly-rectifying channel J3 , GIRK1 , KGA , KGB1 , potassium channel inwarding rectifying channel subfamily J member 3 , potassium channel subunit Kir3.1 type 3 delta , inward rectifying potassium channel, Kir3.1